Mitral Annular Velocities Generated by Speckle Tracking Imaging: Reproducibility and Correlation with Tissue Doppler Velocities


Address for correspondence and reprint requests: Smadar Kort, M.D., Division of Cardiovascular Medicine, Stony Brook University Medical Center, Health Sciences Center T16-080, Stony Brook, NY 11794. Fax: 631-444-1054; E-mail:


Background: Early diastolic mitral annular velocities (E′) are routinely generated by tissue Doppler imaging (TDI), an angle-dependent technique. Velocity vector imaging (VVI) lacks this limitation. Normal VVI E′ values and their correlation with TDI E′ are unknown. Methods: E′ by VVI and TDI were compared in 100 patients. Results: VVI velocities are lower and correlate moderately with TDI velocities for medial E′ (r = 0.405) and mildly for lateral E′ (r = 0.278) and are image quality dependent. In patients with diastolic or systolic dysfunction, no correlation was found. E′ < 0.06 m/s by VVI for the medial and lateral annulus can detect abnormal diastolic function with sensitivity of 90% and 77%, respectively, and with specificity of 56% and 52%, respectively. Conclusions: E′ by VVI is lower than by TDI with a poor agreement between the measurements, which are therefore not interchangeable. Although VVI can be performed offline, this method is dependent on image quality. (Echocardiography 2010;27:637-643)