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Keywords:

  • Factor V Leiden;
  • hypercoagulability;
  • oral contraceptives;
  • venous thromboembolism

Factor V Leiden is the most common genetic cause of primary and recurrent venous thromboembolism in women. It is an inherited thrombophilia that results from a genetic mutation. A college-aged woman who presented for care and had a positive family history of venous thrombosis tested positive for Factor V Leiden. Laboratory tests and plans for continuing care are discussed.