Costs of managing anemia with erythropoiesis-stimulating agents during hemodialysis: A time and motion study
Version of Record online: 3 OCT 2008
© 2008 The Authors. Journal compilation © 2008 International Society for Hemodialysis
Volume 12, Issue 4, pages 441–449, October 2008
How to Cite
SCHILLER, B., DOSS, S., DE COCK, E., DEL AGUILA, M. A. and NISSENSON, A. R. (2008), Costs of managing anemia with erythropoiesis-stimulating agents during hemodialysis: A time and motion study. Hemodialysis International, 12: 441–449. doi: 10.1111/j.1542-4758.2008.00308.x
- Issue online: 3 OCT 2008
- Version of Record online: 3 OCT 2008
- Manuscript received March 2008; revised May 2008.
- Personnel time;
- resource utilization;
- drug administration;
- erythropoiesis-stimulating agent (ESAs)
Use of erythropoiesis-stimulating agents (ESAs) presents a significant time and cost burden in the management of anemia of chronic kidney disease (CKD). We conducted a prospective, observational, activity-based costing study to estimate the health care personnel time and resulting direct medical costs associated with administering epoetin 3 times weekly to patients with end-stage renal disease on dialysis. The study was conducted at 5 US hemodialysis centers. The personnel time and costs were derived from time and motion observations. Predicted time and cost savings were modeled for switching patients to once-monthly ESA therapy. Patients also completed a survey questionnaire to assess their level of CKD knowledge and information needs. Total per-patient-per-year (PPPY) time expended on anemia management with epoetin averaged 608 minutes (range 512–915 minutes), with an average PPPY cost of $548 (range $342–$651). Use of a once-monthly ESA, compared with epoetin, could decrease average PPPY time expenditure by 79% (127 minutes [range 96–173 minutes]) and reduce PPPY costs by 81% ($104 [range $79–$136]). The patient questionnaire reported insufficient education on CKD. Use of a once-monthly ESA to correct anemia in dialysis patients may provide substantial time, resource, and cost savings compared with current treatment practices.