This research was supported by grants from American Nurses Foundation, Oncology Nursing Foundation, Regional West Foundation, and Sigma Theta Tau International small grants program.
Testing an Intervention for Preventing Osteoporosis in Postmenopausal Breast Cancer Survivors
Article first published online: 23 APR 2004
Journal of Nursing Scholarship
Volume 35, Issue 4, pages 333–338, December 2003
How to Cite
Waltman, N. L., Twiss, J. J., Ott, C. D., Gross, G. J., Lindsey, A. M., Moore, T. E. and Berg, K. (2003), Testing an Intervention for Preventing Osteoporosis in Postmenopausal Breast Cancer Survivors. Journal of Nursing Scholarship, 35: 333–338. doi: 10.1111/j.1547-5069.2003.00333.x
- Issue published online: 23 APR 2004
- Article first published online: 23 APR 2004
- Accepted for publication December 3, 2002.
- breast cancer survivors;
- strength training exercises
Purpose: To test a 12-month multicomponent intervention for preventing or treating osteoporosis in 21 postmenopausal women who had completed treatment (except Tamoxifen) for breast cancer, and for whom hormone replacement therapy (HRT) was contraindicated.
Design: Pilot intervention study.
Methods: The intervention consisted of home-based strength and weight training exercises, 5 or 10 mg alendronate per day, 1500 mg calcium per day, 400 IU vitamin D per day, education on osteoporosis, and facilitative strategies to promote adherence to the intervention. Outcome measures were: adherence to the intervention, dynamic balance, muscle strength, and bone mineral density (BMD) of the hip, spine, and forearm.
Findings and Conclusions: Adherence to calcium, vitamin D, and alendronate therapy was above 95%, and adherence to strength training exercises was above 85%. Over the 12 months, the 21 participants had significant improvements in dynamic balance, muscle strength for hip flexion, hip extension, and knee flexion, and BMD of the spine and hip. Participants had a significant decrease in BMD of the forearm. Three of the 21 women who had measurable bone loss at baseline had normal BMD after 12 months of the intervention.