Genomics for Health in Preconception and Prenatal Periods
Article first published online: 26 FEB 2007
Journal of Nursing Scholarship
Volume 39, Issue 1, pages 4–9, March 2007
How to Cite
Dolan, S., Biermann, J. and Damus, K. (2007), Genomics for Health in Preconception and Prenatal Periods. Journal of Nursing Scholarship, 39: 4–9. doi: 10.1111/j.1547-5069.2007.00136.x
- Issue published online: 26 FEB 2007
- Article first published online: 26 FEB 2007
- Accepted for publication August 9, 2006.
- genetic testing;
Purpose: To review and report changes in genomic-based knowledge and care during the preconception and prenatal periods.
Design: Integrative review of relevant medical and nursing literature.
Findings: Client education and counseling are needed to understand genomic information and provide guidance in interpreting this information and making decisions. The factors that influence decision-making about testing and acting on test results constitute a complex process that has not been well studied. Family history is an important tool for obtaining genomic information and can assist women and families in understanding risk preconceptionally and prenatally. Genomic research has enhanced understanding of the mechanisms of birth defects such as neural tube defect and will likely provide research opportunities to better understand complex perinatal outcomes such as preterm birth.
Conclusions: Research, education, advocacy, and anticipatory guidance are needed as women and families obtain more genetic and genomic information before and during pregnancy. All nurses will be involved in helping patients use genetic and genomic information to understand risk and to develop strategies to modify risk, and in translating the expanding array of genomic information to improve birth outcomes.