Modifiable Lifestyle and Environmental Risk Factors Affecting the Retinal Microcirculation
Version of Record online: 21 DEC 2011
© 2011 John Wiley & Sons Ltd
Special Issue: Clinical Microcirculation
Volume 19, Issue 1, pages 29–36, January 2012
How to Cite
SERRE, K. and SASONGKO, M. B. (2012), Modifiable Lifestyle and Environmental Risk Factors Affecting the Retinal Microcirculation. Microcirculation, 19: 29–36. doi: 10.1111/j.1549-8719.2011.00121.x
- Issue online: 21 DEC 2011
- Version of Record online: 21 DEC 2011
- Accepted manuscript online: 8 JUL 2011 01:41PM EST
- Received 07 June 2011; accepted 30 June 2011.
- retinal microcirculation;
- modifiable cardiovascular risk factors
Please cite this paper as: Serre and Sasongko (2012). Modifiable Lifestyle and Environmental Risk Factors Affecting the Retinal Microcirculation. Microcirculation 19(1), 29–36.
Structural changes within the human retinal vasculature may reflect systemic vascular changes associated with various cardiovascular and metabolic disorders. Recent data suggest that systemic exposure from a range of modifiable lifestyle and environmental risk factors (e.g., diet, physical activity, and smoking) may affect the morphology of the retinal vasculature. Being easily accessible and non-invasively visualized, the retinal microvasculature therefore can be a clinically useful biomarker of reversible sub-clinical physiologic deviation of the systemic circulation as results of such unfavorable exposures. Importantly, quantitative analysis of the retinal microvasculature may be utilized as a prognostic tool, allowing for targeted vascular therapies before the onset of overt cardiovascular and metabolic disorders. This review summarizes the modifiable lifestyle and environmental risk factors that affect retinal microvascular structure and the possible clinical implications of such relationships.