The multi-walled (B, N)-codoped titanate nanotubes (TNTs) have been prepared via a simple hydrothermal route. Such (B, N)-codoped TNTs showed a decrease in band gap energy as compared with the undoped TNTs. The effect of the doping amounts of B and N on the photocatalytic activity of TNTs was studied. Among the as-prepared samples, (1% B, 1% N)-codoped TNTs exhibited the best photocatalytic activity for methyl orange decomposition under Ultraviolet–Visible (UV–Vis) light irradiation. The photocatalytic activity of (1% B, 1% N)-codoped TNTs is twice as high as that of the undoped TNTs.