Flower-like hydroxyapatite (HA) was prepared by a solvothermal method using calcined eggshells as calcium source and hydrogen peroxide/N,N-dimethylformamide (DMF) as solvent. The products are characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and Scanning electron microscopy (SEM). All the above-mentioned instrumental analysis such as XRD and FT-IR showed the purity of HA. The SEM indicates that the as-obtained flower-like HA are composed of microsheets. These nanosheets interleaved each other to form the uniform flower-like morphology. The influence of precipitation temperature and ratio of hydrogen peroxide to DMF were systematically investigated by SEM analysis.