Hyperechogenicity of the Substantia Nigra in Parkinson's Disease
Article first published online: 12 APR 2007
Journal of Neuroimaging
Volume 17, Issue 2, pages 164–167, April 2007
How to Cite
Ressner, P., Školoudík, D., Hluštík, P. and Kaňovský, P. (2007), Hyperechogenicity of the Substantia Nigra in Parkinson's Disease. Journal of Neuroimaging, 17: 164–167. doi: 10.1111/j.1552-6569.2007.00114.x
- Issue published online: 12 APR 2007
- Article first published online: 12 APR 2007
- Received December 14, 2006, and in revised form December 14, 2006. Accepted for publication December 18, 2006.
- Parkinson's disease;
- substantia nigra;
- ultrasound of the brain stem
Substantia nigra (SN) was assessed by transcranial sonography (TCS) in 47 Parkinson's disease (PD) patients and in 39 healthy volunteers. A semiquantitative echogenicity scale was created with arbitrary values ranging from 1 to 5, zones with grade ≥3 and larger than 0.19 cm2 were recorded as hyperechogenic SN. TCS examination of SN as a diagnostic test for PD in our study showed 87.2% sensitivity and 94.9% specificity.