• Carbohydrate-deficient transferrin;
  • Fetal alcohol prevention;
  • Prenatal alcohol use

Objective: To compare two prenatal alcohol use screening instruments with a physiologic measure of prenatal alcohol use.

Design: Retrospective comparison of the Prenatal Alcohol Use Interview (PAUI) and the ACOG Antepartum Record with CDTect.

Setting: An inner-city, high-volume, prenatal clinic.

Participants: Fifty-six women selected and enrolled at their first prenatal visits.

Main Outcome Measure: An assessment of relative sensitivity and specificity of two prenatal alcohol use screening instruments.

Results: Women identified as Drinkers by the CDTect were more likely to be identified as Drinkers by the PAUI (59%) than by the ACOG Antepartum Record (19%). Also, the PAUI had a lower false negative rate (41%) than the ACOG record (80%). That is, the PAUI was less likely to identify as Quitters women the CDTect identified as Drinkers than was the ACOG record.

Conclusion: The PAUI is a more sensitive screen than the ACOG record and should be the instrument preferred for screening prenatal alcohol use.