Rapid Response to Stroke Symptoms: The Delay in Accessing Stroke Healthcare (DASH) Study


Cardiovascular Disease Program, Department of Epidemiology, University of North Carolina, CB #7400, McGavran-Greenberg Hall, Chapel Hill, NC 27599–7400. Fax: 919–966–9800; e-mail: wayne.rosamond@unc.edu


Objective: To assess the determinants of prehospital delay for patients with presumed acute cerebral ischemia (ACI) in order to provide the background necessary to develop interventions to shorten such delays.

Methods: A prospective registry of patients presenting to the ED with signs and symptoms of stroke was established at a university hospital from July 1995 to March 1996. Trained nurses performed a structured ED interview, which assessed prehospital delay and potential confounders.

Results: The median delay (interquartile range) from symptom onset to ED arrival for all patients seeking care for stroke-like symptoms (n= 152) was 3.0 hours (1.5–7.8 hr). The median delay from symptom onset to ED arrival was less in cases where a witness first recognized that there was a serious problem than it was when the patient first identified the problem. A heightened sense of urgency by the patient about his or her symptoms, and use of 911/emergency medical services (EMS) transport were also associated with rapid arrival in the ED within 3 hours of symptom onset. After adjusting for all predictor variables in a multivariable logistic regression model, only recognition of symptoms by a witness and calling 911/EMS transport remained statistically significant.

Conclusions: These data suggest that future efforts to intervene on prolonged prehospital delay for patients with ACI should include strategies for the community as a whole as well as persons at risk for stroke and should reinforce the use of 911 and EMS transport.