The Analysis of Illicit Methaqualone Containing Preparations by Gas Chromatography–Mass Spectrometry for Forensic Purposes
Article first published online: 8 MAR 2006
Journal of Forensic Sciences
Volume 51, Issue 2, pages 376–380, March 2006
How to Cite
Grové, A. A., Rohwer, E. R., Laurens, J. B. and Vorster, B. C. (2006), The Analysis of Illicit Methaqualone Containing Preparations by Gas Chromatography–Mass Spectrometry for Forensic Purposes. Journal of Forensic Sciences, 51: 376–380. doi: 10.1111/j.1556-4029.2006.00053.x
- Issue published online: 8 MAR 2006
- Article first published online: 8 MAR 2006
- Received 7 May 2005; and in revised form 22 Aug. 2005; accepted 1 Oct. 2005; published 9 Feb. 2006.
- forensic science;
- forensic chemistry;
- quantitative analysis;
- gas chromatography–mass spectrometry
ABSTRACT: A validated gas chromatographic–mass spectrometric method for quantitative analysis of methaqualone (MTQ) in illicit preparations is reported. The method proved to have a coefficient of variation of below 5%. Four batches of seized tablets, two pairs with similar imprints, were analyzed. It was found that the average MTQ concentration in all four batches of tablets differed significantly (p=0.01) rendering it impossible to conclude that, on the basis of MTQ concentration alone, the batches with a similar logo originated from the same manufacturer or manufacturing batch. Conversely, it can be said that in this case, the four batches originated from either different clandestine laboratories or manufacturing batches.