The opinions and assertions contained herein are solely those of the authors and are not to be construed as official or as views of the U.S. Department of Defense, the U.S. Department of the Army, or the U.S. Department of the Navy.
Application of Low Copy Number STR Typing to the Identification of Aged, Degraded Skeletal Remains*
Article first published online: 18 OCT 2007
Journal of Forensic Sciences
Volume 52, Issue 6, pages 1322–1327, November 2007
How to Cite
Irwin, J. A., Leney, M. D., Loreille, O., Barritt, S. M., Christensen, A. F., Holland, T. D., Smith, B. C. and Parsons, T. J. (2007), Application of Low Copy Number STR Typing to the Identification of Aged, Degraded Skeletal Remains. Journal of Forensic Sciences, 52: 1322–1327. doi: 10.1111/j.1556-4029.2007.00561.x
- Issue published online: 18 OCT 2007
- Article first published online: 18 OCT 2007
- Received 24 Dec. 2006; and in revised form 29 April 2007; accepted 29 April 2007; published 21 Dec. 2007.
- forensic sciences;
- DNA typing;
- low copy number;
- Y chromosome;
- mitochondrial DNA;
- short tandem repeat;
- degraded skeletal remains
Abstract: Low copy number (LCN) STR typing was successfully applied to four interesting cases during developmental validation of the approach for degraded skeletal remains. Specific questions were addressed in each case, with the acquisition of STR data largely serving as additional confirmatory or investigatory information in any specific situation, and not necessarily providing the definitive evidence to establish identity. The cases involve missing U.S. service members from World War I, World War II, and the Vietnam War. The variety of these cases, in terms of the questions addressed, the age of the remains, and the type of reference material available for comparison, demonstrates the broad utility of LCN STR typing in the identification of degraded skeletal remains from missing persons.