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GeneMarker® HID: A Reliable Software Tool for the Analysis of Forensic STR Data

Authors


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Mitchell M. Holland, Ph.D., M.Sc.
Director of the Forensic Science Program
Associate Professor of Biochemistry and Molecular Biology
Penn State University 107 Whitmore Laboratory
University Park, PA 16802
E-mail: mmh20@psu.edu

Abstract

Abstract:  GeneMarker® HID was assessed as a software tool for the analysis of forensic short tandem repeat (STR) data and as a resource for analysis of custom STR multiplexes. The software is easy to learn and use, and includes design features that have the potential to reduce user fatigue. To illustrate reliability and accuracy, STR data from both single-source and mixture profiles were analyzed and compared to profiles interpreted with another software package. A total of 1898 STR profiles representing 28,470 loci and more than 42,000 alleles were analyzed with 100% concordance. GeneMarker HID was also used to successfully analyze data generated from a custom STR multiplex, with simplified and rapid implementation. Finally, the impact of the user-friendly design features of the software was assessed through a time scale study. The results suggest that laboratories can reduce the time required for data analysis by at least 25% when using GeneMarker HID.

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