Supported by grants from the Italian National Institute of Health and from the National Department of Drug Politics.
TECHNICAL NOTE CRIMINALISTICS
Investigations into the Hypothesis of Transgenic Cannabis*
Article first published online: 28 DEC 2011
© 2011 American Academy of Forensic Sciences
Journal of Forensic Sciences
Volume 57, Issue 3, pages 718–721, May 2012
How to Cite
Cascini, F. (2012), Investigations into the Hypothesis of Transgenic Cannabis. Journal of Forensic Sciences, 57: 718–721. doi: 10.1111/j.1556-4029.2011.02021.x
- Issue published online: 19 APR 2012
- Article first published online: 28 DEC 2011
- Received 9 Nov. 2010; and in revised form 22 Feb. 2011; accepted 12 Mar. 2011.
- forensic science;
Abstract: The unusual concentration of cannabinoids recently found in marijuana samples submitted to the forensic laboratory for chemical analysis prompted an investigation into whether genetic modifications have been made to the DNA of Cannabis sativa L. to increase its potency. Traditional methods for the detection of genetically modified organisms (GMO) were used to analyze herbal cannabis preparations. Our analyses support the hypothesis that marijuana samples submitted to forensic laboratories and characterized by an abnormal level of Δ9-THC are the product of breeding selection rather than of transgenic modifications. Further, this research has shown a risk of false positive results associated with the poor quality of the seized samples and probably due to the contamination by other transgenic vegetable products. On the other hand, based on these data, a conclusive distinction between the hypothesis of GMO plant contamination and the other of genetic modification of cannabis cannot be made requiring further studies on comparative chemical and genetic analyses to find out an explanation for the recently detected increased potency of cannabis.