CASE REPORT TOXICOLOGY
Drug-Facilitated Sexual Assault Using Tetrahydrozoline
Article first published online: 28 DEC 2011
© 2011 American Academy of Forensic Sciences
Journal of Forensic Sciences
Volume 57, Issue 3, pages 835–838, May 2012
How to Cite
Spiller, H. A. and Siewert, D. J. (2012), Drug-Facilitated Sexual Assault Using Tetrahydrozoline. Journal of Forensic Sciences, 57: 835–838. doi: 10.1111/j.1556-4029.2011.02026.x
- Issue published online: 19 APR 2012
- Article first published online: 28 DEC 2011
- Received 21 Oct. 2010; and in revised form 15 Mar. 2011; accepted 27 Mar. 2011.
- forensic science;
- drug-facilitated sexual assault;
- urine quantification;
- gas chromatography mass spectrometry
Abstract: Drug-facilitated sexual assault (DFSA) has been defined as the use of a chemical agent to facilitate a sexual assault. We report two cases of the use of tetrahydrozoline for DFSA. We believe this is the first report with urinary quantification of tetrahydrozoline levels postassault. Blood and urine were obtained c. 20 h postexposure in two cases of reported DFSA. Tetrahydrozoline was not detected in blood but was identified in urine in both victims. After initial identification in the urine using the 2010 update to the AAFS mass spectrometry database library, tetrahydrozoline was quantified at 114 and 150 ng/mL, respectively, using GC/MS. Two unique clinical features reported in these cases were intermittent periods of consciousness and postexposure vomiting. Use of GC/MS was successful in identifying tetrahydrozoline in the 100 ng/mL range up to 20 h postexposure. For victims with late presentation, urine may be a better sample for evaluation for tetrahydrozoline.