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Appendix S1: Computer code.

Appendix S2: Proof of symmetry of the proposal distribution for randomly selecting a new point on an evolutionary tree.

Appendix S3: Complete results from simulation test of the method.

Table S1. Summary of results from simulation 1., .

Table S2. Summary of results from simulation 2.

Table S3. Summary of results from simulation 3.

Table S4. Summary of results from simulation 3.

Table S5. Summary of results from simulations of trees with number of taxa N = 30.

Table S6. Summary of results from simulations of trees with number of taxa N = 50.

Table S7. Summary of results from simulations of trees with number of taxa N = 70.

Table S8. Summary of results from simulations of trees with number of taxa N = 200.

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