Appendix S1. Supplementary Methods and Results.

Table S1. List of taxa and Genbank Accession numbers.

Table S2. Outgroups.

Table S3. Medusa characters used in the phylogenetic analysis in Figure 8.

Table S4. Species grown in laboratory conditions.

Table S5. Ontogeny of colony form determined by growing 13 species in four genera.

Table S6. Number of substitution rates, nucleotide frequencies, rate models and invariant sites for each gene.

Table S7. Host specificity BiSSE analysis.

Figure S1. Majority-rule consensus tree.

Figure S2. Partitioned Garli Maximum Likelihood analysis and bootstrap support.

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