The authors contributed equally to this work.
LOST IN THE MAP
Article first published online: 10 OCT 2012
© 2012 The Author(s). Evolution© 2012 The Society for the Study of Evolution.
Volume 67, Issue 2, pages 305–314, February 2013
How to Cite
Travisano, M. and Shaw, R. G. (2013), LOST IN THE MAP. Evolution, 67: 305–314. doi: 10.1111/j.1558-5646.2012.01802.x
- Issue published online: 28 JAN 2013
- Article first published online: 10 OCT 2012
- Accepted manuscript online: 18 SEP 2012 03:31AM EST
- Received July 24, 2012 Accepted August 24, 2012
- Evolutionary explanation;
- genotype to phenotype map;
- QTL mapping
Organismal development and evolution are complex, multifaceted processes that depend intimately on context. They are subject to environmental influences, chance appearance and fixation of mutations, and numerous other idiosyncrasies. Genomics is detailing the molecular signature of effects of these mechanisms on phenotypes, but because numerous distinct evolutionary explanations can produce a given genomic pattern, the molecular details, rather than elucidating process, typically distract from explanatory insight and contribute little to predictive capability. While genomic research has burgeoned, direct study of evolutionary and developmental processes has lagged. We advocate for reinvigoration of direct study of process, along with refocusing of attention on questions of broad biological import, as more productive of urgently needed insights, which genomic approaches are not providing.