MALE-BIASED FITNESS EFFECTS OF SPONTANEOUS MUTATIONS IN DROSOPHILA MELANOGASTER
Version of Record online: 29 NOV 2012
© 2012 The Author(s). Evolution© 2012 The Society for the Study of Evolution.
Volume 67, Issue 4, pages 1189–1195, April 2013
How to Cite
Sharp, N. P. and Agrawal, A. F. (2013), MALE-BIASED FITNESS EFFECTS OF SPONTANEOUS MUTATIONS IN DROSOPHILA MELANOGASTER. Evolution, 67: 1189–1195. doi: 10.1111/j.1558-5646.2012.01834.x
- Issue online: 3 APR 2013
- Version of Record online: 29 NOV 2012
- Accepted manuscript online: 29 OCT 2012 01:40PM EST
- Received June 16, 2012 Accepted October 9, 2012 Data Archived: Dryad doi:10.5061/dryad.368nr
- population genetics;
- sexual selection
In populations with males and females, sexual selection may often represent a major component of overall selection. Sexual selection could act to eliminate deleterious alleles in concert with other forms of selection, thereby improving the fitness of sexual populations. Alternatively, the divergent reproductive strategies of the sexes could promote the maintenance of sexually antagonistic variation, causing sexual populations to be less fit. The net impact of sexual selection on fitness is not well understood, due in part to limited data on the sex-specific effects of spontaneous mutations on total fitness. Using a set of mutation accumulation lines of Drosophila melanogaster, we found that mutations were deleterious in both sexes and had larger effects on fitness in males than in females. This pattern is expected to reduce the mutation load of sexual females and promote the maintenance of sexual reproduction.