It was hypothesized that repeated exposure to humorous material reduces distress, pain, and medication following surgery. This hypothesis was tested in a field experiment by randomly assigning 78 postsurgical patients to either a control group or 1 of 8 experimental groups formed by the factorial crossing of type of videotape (humorous vs. serious), perceived control (choice vs. no choice), and expectation (positive vs. none). Multivariate analyses of variance disclosed that humor reduced requests for minor medication, combined with expectations to reduce pain, but increased use of heavy analgesic when patients were deprived of choice. Although more research needs to be done, the findings suggest that hospital patients benefit from humorous and distracting material when exposure is voluntary.