This research examined the independent and combined influence of workgroup drinking norms and safety climate on the cognitive outcomes of prevention. Employees from 72 workgroups (n = 347) were randomly assigned to attend 1 of 2 training conditions or a control group that did not receive training until after follow-up questionnaires. Results from hierarchical regression analyses showed there was a significant effect of the interaction between safety climate, drinking norms, and training on beliefs that policy and the employee assistance program are effective. Informational training was least effective for employees from relatively temperate workgroups. Team awareness was less effective for employees from tolerant groups. Employees might benefit more from interventions tailored to individual and workgroup cultural factors.