Numerous studies have found that individuals' levels of job strain are consistently and strongly related to turnover intention. The present study examined whether the supervisor—which is one of the most important interorganizational relationships that employees have—might buffer the strain/turnover-intention relationship. We employed the conservation of resources theory and proposed a number of hypotheses related to aspects of the supervisor–subordinate relationship moderating the strain–intention to turnover relationship. We tested these relationships using a sample of 231 employees, who were computer workers from a number of different organizations. Our results showed support for several hypothesized supervisor-related moderators.