Despite similarities between sexism, racism, sexual prejudice, ageism, classism, and religious intolerance, investigators do not routinely investigate these intolerant beliefs simultaneously. The purpose of this project was to create a brief, psychometrically sound measure of intolerance reflecting these 6 constructs. Data from existing measures (Attitudes Toward Women Scale, Neosexism Scale, Modern and Old-Fashioned Racism Scale, Modern Homophobia Scale, Frabroni Scale of Ageism, Economic Beliefs Scale, and M-GRISM) and from items created by the authors were obtained from several college samples to create the Intolerant Schema Measure (ISM). Results support the internal consistency, test–retest reliability, and factor structure of the questionnaire. Expected relationships between measured concepts, social dominance, social desirability, and across key demographic groups support the validity of the instrument.