The Pathophysiology of Cardiovascular Disease in Diabetes Mellitus and the Future of Therapy

  1. Joseph Emmanuel Thomas MD,
  2. JoAnne Micale Foody MD

Article first published online: 1 JUN 2007

DOI: 10.1111/j.1559-4564.2007.06046.x

Issue

Journal of the CardioMetabolic Syndrome

Journal of the CardioMetabolic Syndrome

Volume 2, Issue 2, pages 108–113, Spring 2007

Additional Information

How to Cite

Thomas, J. E. and Foody, J. M. (2007), The Pathophysiology of Cardiovascular Disease in Diabetes Mellitus and the Future of Therapy. Journal of the CardioMetabolic Syndrome, 2: 108–113. doi: 10.1111/j.1559-4564.2007.06046.x

Author Information

  1. From the Division of Internal Medicine, Department of Cardiology, Yale School of Medicine, New Haven, CT

*JoAnne Micale Foody, MD, Division of Internal Medicine, Department of Cardiology, Yale School of Medicine, 333 Cedar Street, PO Box 208025, New Haven, CT 06520-8025 E-mail: joanne.foody@yale.edu

Publication History

  1. Issue published online: 1 JUN 2007
  2. Article first published online: 1 JUN 2007
  3. Manuscript received November 7, 2006; accepted January 19, 2007

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Diabetes mellitus is a complex disease with several metabolic abnormalities leading to varied, interconnected endothelial and vascular dysfunction and resulting in accelerated atherosclerosis. Cardiovascular disease is the main cause of mortality in patients with diabetes. Apart from traditional therapy for control of hyperglycemia and other associated comorbidities, various newer therapies are being investigated to fight atherosclerosis at a molecular level. In this review, the authors briefly describe the pathophysiology of cardiovascular disease in patients with diabetes mellitus and the future of therapy.

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