Editor: Willem van Leeuwen
Spotted fever rickettsioses in southern and eastern Europe
Article first published online: 24 JAN 2007
FEMS Immunology & Medical Microbiology
Volume 49, Issue 1, pages 2–12, February 2007
How to Cite
Brouqui, P., Parola, P., Fournier, P. E. and Raoult, D. (2007), Spotted fever rickettsioses in southern and eastern Europe. FEMS Immunology & Medical Microbiology, 49: 2–12. doi: 10.1111/j.1574-695X.2006.00138.x
- Issue published online: 24 JAN 2007
- Article first published online: 24 JAN 2007
- Received 9 March 2006; revised 14 June 2006; accepted 22 June 2006.First published online January 2007.
- spotted fever Rickettsia;
Mediterranean spotted fever due to Rickettsia conorii conorii was thought, for many years, to be the only tick-borne rickettsial disease prevalent in southern and eastern Europe. However, in recent years, six more species or subspecies within the spotted fever group of the genus Rickettsia have been described as emerging pathogens in this part of the world. Tick-borne agents include Rickettsia conorii israelensis, Rickettsia conorii caspia, Rickettsia aeschlimannii, Rickettsia slovaca, Rickettsia sibirica mongolitimonae and Rickettsia massiliae. Many Rickettsia of unknown pathogenicity have also been detected from ticks and could represent potential emerging pathogens to be discovered in the future. Furthermore, a new spotted fever rickettsia, Rickettsia felis, was found to be associated with cat fleas and is an emerging human pathogen. Finally, the mite-transmitted Rickettsia akari, the agent of rickettsialpox, is also known to be prevalent in Europe. We present here an overview of these rickettsioses, focusing on emerging diseases.