Editor: George Mendz
Knockout mutagenesis of the kpsE gene of Campylobacter jejuni 81116 and its involvement in bacterium–host interactions
Article first published online: 8 JAN 2007
FEMS Immunology & Medical Microbiology
Volume 49, Issue 1, pages 149–154, February 2007
How to Cite
Bachtiar, B. M., Coloe, P. J. and Fry, B. N. (2007), Knockout mutagenesis of the kpsE gene of Campylobacter jejuni 81116 and its involvement in bacterium–host interactions. FEMS Immunology & Medical Microbiology, 49: 149–154. doi: 10.1111/j.1574-695X.2006.00182.x
- Issue published online: 24 JAN 2007
- Article first published online: 8 JAN 2007
- Received 26 January 2006; revised 3 September 2006; accepted 29 September 2006.First published online January 2007.
- Campylobacter jejuni;
- kpsE gene;
- bacterium–host interaction
Campylobacter jejuni is a common cause of bacterial enteritis. The surface capsular polysaccharides are important for this bacterium to survive in the environment, but little is known about their involvement in bacterium–host interactions. This study showed that the C. jejuni capsular polysaccharides play an important role in adherence to and invasion of human embryonic epithelial cells. However, no significant role of capsular polysaccharides was shown in colonization of the chicken gut.