Editor: Willem van Leeuwen
Osteomyelitis and the role of biofilms in chronic infection
Article first published online: 13 DEC 2007
FEMS Immunology & Medical Microbiology
Volume 52, Issue 1, pages 13–22, January 2008
How to Cite
Brady, R. A., Leid, J. G., Calhoun, J. H., Costerton, J. W. and Shirtliff, M. E. (2008), Osteomyelitis and the role of biofilms in chronic infection. FEMS Immunology & Medical Microbiology, 52: 13–22. doi: 10.1111/j.1574-695X.2007.00357.x
- Issue published online: 13 DEC 2007
- Article first published online: 13 DEC 2007
- Received 2 July 2007; revised 28 September 2007; accepted 30 September 2007.First published online 13 December 2007.
- Staphylococcus aureus
Understanding the mechanisms implicated in the initial attachment, development, and maturation of a biofilm phenotype are of tremendous importance for their effect on the medical, industrial, and public health arenas. This review explores the current understanding of the nature of biofilms and the impact that molecular interactions between the bacteria themselves, as well as between bacteria and the host, may have on biofilm development and phenotype using the nonmotile Gram-positive coccus, Staphylococcus aureus, as an example.