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Keywords:

  • Corynebacterium;
  • skin flora;
  • antibiotic resistant

Abstract Production of a bacteriocin-like substance associated with the presence of a plasmid, pKW4, of Mr 9.5 × 106 has been demonstrated in a JK-type coryneform. The bacteriocin has a narrow spectrum of activity, acting predominantly against JKs, Corynebacterium bovis and Rhodococcus equi. A restriction endonuclease map of the plasmid has been constructed.