Characterisation of a highly repeated DNA sequence from Mycobacterium bovis


Correspondence to: T.J. Doran, CSIRO Division of Animal Health, Animal Health Research Laboratory, Private Bag No. 1, Parkville, Vic. 3052, Australia.


Abstract We report characterisation of a novel repeat sequence from a Mycobacterium bovis genomic library. The highly repeated sequence belongs to a family consisting of a 24 base pair (bp) direct repeat (DR), that appears to be organized into clusters on the chromosome. We classify the 24-bp DR into the group of prokaryotic DNA repeats known as the interspersed repetitive sequence elements. The 24-bp DR will be of potential use as a DNA fingerprinting tool in epidemiological studies of M. bovis.