Structure and partitioning of bacterial DNA: determined by a balance of compaction and expansion forces?
Article first published online: 17 JAN 2006
FEMS Microbiology Letters
Volume 131, Issue 3, pages 235–242, September 1995
How to Cite
Woldringh, C. L., Jensen, P. R. and Westerhoff, H. V. (1995), Structure and partitioning of bacterial DNA: determined by a balance of compaction and expansion forces?. FEMS Microbiology Letters, 131: 235–242. doi: 10.1111/j.1574-6968.1995.tb07782.x
- Issue published online: 17 JAN 2006
- Article first published online: 17 JAN 2006
- (Received 18 May 1995, Revised 19 June 1995, Accepted 19 June 1995)
- DNA supercoiling;
- Nucleoid structure;
- Coupled transcription/translation;
- Protein translocation
Abstract The mechanisms that determine chromosome structure and chromosome partitioning in bacteria are largely unknown. Here we discuss two hypotheses: (i) the structure of the Escherichia coli nucleoid is determined by DNA binding proteins and DNA supercoiling, representing a compaction force on the one hand, and by the coupled transcription/translation/ translocation of plasma membrane and cell wall proteins, representing an expansion force on the other hand; (ii) the two forces are important for the partitioning process of chromosomes.