A comparison of gene organization in the zwf region of the genomes of the cyanobacteria Synechococcus sp. PCC 7942 and Anabaena sp. PCC 7120

  1. Julie Newman,
  2. Haydar Karakaya,
  3. David J. Scanlan,
  4. Nicholas H. Mann*

Article first published online: 17 JAN 2006

DOI: 10.1111/j.1574-6968.1995.tb07882.x

Issue

FEMS Microbiology Letters

FEMS Microbiology Letters

Volume 133, Issue 1-2, pages 187–193, November 1995

Additional Information

How to Cite

Newman, J., Karakaya, H., Scanlan, D. J. and Mann, N. H. (1995), A comparison of gene organization in the zwf region of the genomes of the cyanobacteria Synechococcus sp. PCC 7942 and Anabaena sp. PCC 7120. FEMS Microbiology Letters, 133: 187–193. doi: 10.1111/j.1574-6968.1995.tb07882.x

Author Information

  1. Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK

* *Corresponding author. Tel.: +44 (1203) 523 526; Fax; +44 (1203) 523 701; E-mail: nm@dna.bio.warwick.ac.uk

Publication History

  1. Issue published online: 17 JAN 2006
  2. Article first published online: 17 JAN 2006
  3. (Received 21 August 1995, Revised 7 September 1995, Accepted 14 September 1995)

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Keywords:

  • Glucose-6-phosphate dehydrogenase;
  • zwf;
  • Fructose-1,6-bisphosphatase;
  • Synechococcus;
  • Anabaena

Abstract The region of the genome encoding the glucose-6-phosphate dehydrogenase gene zwf was analysed in a unicellular cyanobacterium, Synechococcus sp. PCC 7942, and a filamentous, heterocystous cyanobacterium, Anabaena sp. PCC 7120. Comparison of cyanobacterial zwf sequences revealed the presence of two absolutely conserved cysteine residues which may be implicated in the light/dark control of enzyme activity. The presence in both strains of a gene fbp, encoding fructose-1,6-bisphosphatase, upstream from zwf strongly suggests that the oxidative pentose phosphate pathway in these organisms may function to completely oxidize glucose 6-phosphate to CO2. The amino acid sequence of fructose-1,6-bisphosphatase does not support the idea of its light activation by a thiol/disulfide exchange mechanism. In the case of Anabaena sp. PCC 7120, the tal gene, encoding transaldolase, lies between zwf and fbp.

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