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Keywords:

  • Streptomyces;
  • Angucycline;
  • Landomycin;
  • Biosynthetic gene cluster

Abstract

From a cosmid library of Streptomyces cyanogenus S136, DNA fragments encompassing approximately 35 kb of the presumed landomycin biosynthetic gene cluster were identified and sequenced, revealing 32 open reading frames most of which could be assigned through data base comparison.