Editor: Reggie Lo
Linkage of avian and reproductive tract tropism with sequence divergence adjacent to the 5S ribosomal subunit rrfH of Salmonella enterica
Article first published online: 27 SEP 2006
FEMS Microbiology Letters
Volume 264, Issue 1, pages 48–58, November 2006
How to Cite
Morales, C. A., Gast, R. and Guard-Bouldin, J. (2006), Linkage of avian and reproductive tract tropism with sequence divergence adjacent to the 5S ribosomal subunit rrfH of Salmonella enterica. FEMS Microbiology Letters, 264: 48–58. doi: 10.1111/j.1574-6968.2006.00432.x
- Issue published online: 27 SEP 2006
- Article first published online: 27 SEP 2006
- Received 27 April 2006; revised 26 July 2006; accepted 2 August 2006.First published online September 2006.
- comparative genomics;
- food safety
The 183 bp between the end of the 23S rrlH rRNA gene and the start of the 5S rrfH rRNA gene (ISR-1) and the 197 bp between the end of the rrfH rRNA gene and the start of the transfer RNA aspU (ISR-2) of Salmonella enterica ssp. enterica serotypes Enteritidis, Typhimurium, Pullorum, Heidelberg, Gallinarum, Typhi and Choleraesuis were compared. ISR-1s of D1 serotypes (Pullorum, Gallinarum and Enteritidis), B serotypes (Typhimurium and Heidelberg) and the C2 serotype Newport and the enteric fever pathogens serotype A Paratyphi and serotype D1 Typhi formed three clades, respectively. ISR-2 further differentiated the avian-adapted serotype Gallinarum from avian-adapted Pullorum and Salmonella bongori from S. enterica. The results suggest that serotypes Heidelberg and Choleraesuis share some evolutionary trends with egg-contaminating serotypes. In addition, ISR-1 and ISR-2 sequences that confirm serotype appear to be linked to clinically relevant host associations of the Salmonellae.