Editor: Richard Staples
Detection of quorum-sensing N-acyl homoserine lactone signal molecules by bacterial biosensors
Article first published online: 7 NOV 2006
FEMS Microbiology Letters
Volume 266, Issue 1, pages 1–9, January 2007
How to Cite
Steindler, L. and Venturi, V. (2007), Detection of quorum-sensing N-acyl homoserine lactone signal molecules by bacterial biosensors. FEMS Microbiology Letters, 266: 1–9. doi: 10.1111/j.1574-6968.2006.00501.x
- Issue published online: 8 NOV 2006
- Article first published online: 7 NOV 2006
- Received 18 August 2006; revised 2 October 2006; accepted 9 October 2006.First published online 7 November 2006.
- N-acyl homoserine lactone;
- quorum sensing;
- signal molecules;
- bacterial communication
Many Gram-negative bacteria use N-acyl homoserine lactones (AHLs) as quorum-sensing (QS) signal molecules. AHL QS has been the subject of extensive investigation in the last decade and has become a paradigm for bacterial intercellular signaling. Research in AHL QS has been considerably aided by simple methods devised to detect AHLs using bacterial biosensors that phenotypically respond when exposed to exogenous AHLs. This article reviews and discusses the currently available bacterial biosensors which can be used in detecting and studying the different AHLs.