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A novel strategy for enzymatic synthesis of 4-hydroxyisoleucine: identification of an enzyme possessing HMKP (4-hydroxy-3-methyl-2-keto-pentanoate) aldolase activity

  1. Sergey V. Smirnov1,
  2. Natalya N. Samsonova1,
  3. Anna E. Novikova1,
  4. Nikolay G. Matrosov1,
  5. Natalya Y. Rushkevich1,
  6. Tomohiro Kodera2,
  7. Jun Ogawa3,
  8. Hiroyuki Yamanaka3,
  9. Sakayu Shimizu3

Article first published online: 6 JUN 2007

DOI: 10.1111/j.1574-6968.2007.00783.x

Issue

FEMS Microbiology Letters

FEMS Microbiology Letters

Volume 273, Issue 1, pages 70–77, August 2007

Additional Information

How to Cite

Smirnov, S. V., Samsonova, N. N., Novikova, A. E., Matrosov, N. G., Rushkevich, N. Y., Kodera, T., Ogawa, J., Yamanaka, H. and Shimizu, S. (2007), A novel strategy for enzymatic synthesis of 4-hydroxyisoleucine: identification of an enzyme possessing HMKP (4-hydroxy-3-methyl-2-keto-pentanoate) aldolase activity. FEMS Microbiology Letters, 273: 70–77. doi: 10.1111/j.1574-6968.2007.00783.x

Author Information

  1. 1

    Ajinomoto-Genetika Research Institute, 1st Dorozhny pr. 1, Moscow, Russia

  2. 2

    Institute of Life Sciences, Ajinomoto Co., Inc., Suzuki-cho, Kawasaki-ku, Kawasaki-shi, Japan

  3. 3

    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto, Japan

*Correspondence: Sergey V. Smirnov, Ajinomoto-Genetika Research Institute, 1st Dorozhny pr. 1, Moscow, 113545, Russia. Tel.: +7 495 315 37 66; fax: +7 495 315 00 01; e-mail: servasmi@rol.ru

  1. Editor: Sergio Casella

Publication History

  1. Issue published online: 7 JUN 2007
  2. Article first published online: 6 JUN 2007
  3. Received 16 November 2006; revised 8 April 2007; accepted 26 April 2007.First published online 7 June 2007.

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References

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