Editor: Ross Fitzgerald
Laterally transferred genomic islands in Xanthomonadales related to pathogenicity and primary metabolism
Article first published online: 3 MAR 2008
© 2008 Federation of European Microbiological Societies Published by Blackwell Publishing Ltd
FEMS Microbiology Letters
Volume 281, Issue 1, pages 87–97, April 2008
How to Cite
Lima, W. C., Paquola, A. C.M., Varani, A. M., Van Sluys, M.-A. and Menck, C. F.M. (2008), Laterally transferred genomic islands in Xanthomonadales related to pathogenicity and primary metabolism. FEMS Microbiology Letters, 281: 87–97. doi: 10.1111/j.1574-6968.2008.01083.x
- Issue published online: 4 MAR 2008
- Article first published online: 3 MAR 2008
- Received 10 September 2007; accepted 7 January 2008.First published online February 2008.
- lateral gene transfer;
- horizontal gene transfer;
- genomic islands;
Lateral gene transfer (LGT) is considered as one of the drivers in bacterial genome evolution, usually associated with increased fitness and/or changes in behavior, especially if one considers pathogenic vs. non-pathogenic bacterial groups. The genomes of two phytopathogens, Xanthomonas campestris pv. campestris and Xanthomonas axonopodis pv. citri, were previously inspected for genome islands originating from LGT events, and, in this work, potentially early and late LGT events were identified according to their altered nucleotide composition. The biological role of the islands was also assessed, and pathogenicity, virulence and secondary metabolism pathways were functions highly represented, especially in islands that were found to be recently transferred. However, old islands are composed of a high proportion of genes related to cell primary metabolic functions. These old islands, normally undetected by traditional atypical composition analysis, but confirmed as product of LGT by atypical phylogenetic reconstruction, reveal the role of LGT events by replacing core metabolic genes normally inherited by vertical processes.