Editor: Robert Gunsalus
The yicJI metabolic operon of Escherichia coli is involved in bacterial fitness
Article first published online: 20 APR 2011
© 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved
FEMS Microbiology Letters
Volume 319, Issue 2, pages 180–186, June 2011
How to Cite
Répérant, M., Porcheron, G., Rouquet, G. and Gilot, P. (2011), The yicJI metabolic operon of Escherichia coli is involved in bacterial fitness. FEMS Microbiology Letters, 319: 180–186. doi: 10.1111/j.1574-6968.2011.02281.x
Present address: Philippe Gilot, Faculté de Médecine, Université François Rabelais, EA 3854 Bactéries et Risque Maternofoetal, F-37032 Tours, France.
- Issue published online: 17 MAY 2011
- Article first published online: 20 APR 2011
- Accepted manuscript online: 8 APR 2011 10:35AM EST
- Received 4 November 2010; revised 28 January 2011; accepted 5 April 2011., Final version published online 20 April 2011.
- GPH family;
- frz operon;
The yicJI operon of the common genetic backbone of Escherichia coli codes an α-xylosidase and a transporter of the galactosides–pentoses–hexuronides : cation symporter family. In the extraintestinal pathogenic E. coli strain BEN2908, a metabolic operon (frz) of seven genes is found downstream of the yicI gene. It was proved that frz promotes bacterial fitness under stressful conditions. During this work, we identified a motif containing a palindromic sequence in the promoter region of both the frz and the yicJI operons. We then showed that these two operons are cotranscribed, suggesting a functional relationship. The phenotypes of frz and yicJI deletion mutants were compared. Our results showed that although the yicJI operon is not essential for the life of E. coli, it is necessary for its fitness under all the growth conditions tested.