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  • Abdel-Hadi H, Wooldridge KG, Robinson K & Ala'Aldeen DA (2001) Identification and characterization of App: an immunogenic autotransporter protein of Neisseria meningitidis. Mol Microbiol 41: 611623.
  • Ait-Tahar K, Wooldridge KG, Turner DP, Atta M, Todd I & Ala'Aldeen DA (2000) Autotransporter A protein of Neisseria meningitidis: a potent CD4+T-cell and B-cell stimulating antigen detected by expression cloning. Mol Microbiol 37: 10941105.
  • Altschul SF, Madden TL, Schäffer AA, Zhang J, Zhang Z, Miller W & Lipman DJ (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res 25: 33893402.
  • Ayala P, Lin L, Hopper S, Fukuda M & So M (1998) Infection of epithelial cells by pathogenic neisseriae reduces the levels of multiple lysosomal constituents. Infect Immun 66: 50015007.
  • Ayala BP, Vasquez B, Clary S, Tainer JA, Rodland K & So M (2001) The pilus-induced Ca2+ flux triggers lysosome exocytosis and increases the amount of Lamp1 accessible to Neisseria IgA1 protease. Cell Microbiol 3: 265275.
  • Barenkamp SJ & Leininger E (1992) Cloning, expression, and DNA sequence analysis of genes encoding nontypeable Haemophilus influenzae high-molecular-weight surface-exposed proteins related to filamentous hemagglutinin of Bordetella pertussis. Infect Immun 60: 13021313.
  • Barenkamp SJ & St.Geme III JW (1996) Identification of a second family of high-molecular-weight adhesion proteins expressed by non-typeable Haemophilus influenzae. Mol Microbiol 19: 12151223.
  • Bart A, Feller M & van der Ende A (2004a) Type I secretion mediated resistance to antimicrobial agents in Neisseria meningtidis. Abstract book XIVth International Pathogenic Neisseria Conference, September 5–10, Milwaukee, WI, p. 204.
  • Bart A, Piet JR & van der Ende A (2004b) Different evolutionary histories for the two type I secretion channel-tunnels of Neisseria meningitidis. Abstract book XIVth International Pathogenic Neisseria Conference, September 5–10, Milwaukee, WI, p. 75.
  • Beck SC & Meyer TF (2000) IgA1 protease from Neisseria gonorrhoeae inhibits TNFα-mediated apoptosis of human monocytic cells. FEBS Lett 472: 287292.
  • Benabdelhak H, Kiontke S, Horn C, Ernst R, Blight MA, Holland IB & Schmitt L (2003) A specific interaction between the NBD of the ABC-transporter HlyB and a C-terminal fragment of its transport substrate haemolysin A. J Mol Biol 327: 11691179.
  • Bendtsen JD, Nielsen H, von Heijne G & Brunak S (2004) Improved prediction of signal peptides: signalP 3.0. J Mol Biol 340: 783795.
  • Benz I & Schmidt MA (1992) Isolation and serologic characterization of AIDA-I, the adhesin mediating the diffuse adherence phenotype of the diarrhea-associated Escherichia coli strain 2787 (O126:H27). Infect Immun 60: 1318.
  • Benz I & Schmidt MA (2001) Glycosylation with heptose residues mediated by the aah gene product is essential for adherence of the AIDA-I adhesin. Mol Microbiol 40: 14031413.
  • Berks BC, Palmer T & Sargent F (2003) The Tat protein translocation pathway and its role in microbial physiology. Adv Microb Physiol 47: 187254.
  • Binet R & Wandersman C (1995) Protein secretion by hybrid bacterial ABC-transporters: specific functions of the membrane ATPase and the membrane fusion protein. EMBO J 14: 22982306.
  • Bjerre A, Brusletto B, Rosenqvist E, Namork E, Kierulf P, Øvstebø R, Joø GB & Brandtzaeg P (2000) Cellular activating properties and morphology of membrane-bound and purified meningococcal lipopolysaccharide. J Endotoxin Res 6: 437445.
  • Bowe F, Lavelle EC, McNeela EA, et al. (2004) Mucosal vaccination against serogroup B meningococci: induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin. Infect Immun 72: 40524060.
  • Brandon LD, Goehring N, Janakiraman A, Yan AW, Wu T, Beckwith J & Goldberg MB (2003) IcsA, a polarly localized autotransporter with an atypical signal peptide, uses the Sec apparatus for secretion, although the Sec apparatus is circumferentially distributed. Mol Microbiol 50: 4560.
  • Brandon LD & Goldberg MB (2001) Periplasmic transit and disulfide bond formation of the autotransported Shigella protein IcsA. J Bacteriol 183: 951958.
  • Burns DL (2003) Type IV transporters of pathogenic bacteria. Curr Opin Microbiol 6: 16.
  • Capecchi B, Adu-Bobie J, Di Marcello F, Ciucchi L, Masignani V, Taddei A, Rappuoli R, Pizza M & Aricò B (2005) Neisseria meningitidis NadA is a new invasin which promotes bacterial adhesion to and penetration into human epithelial cells. Mol Microbiol 55: 687698.
  • Cascales E & Christie PJ (2003) The versatile bacterial type IV secretion systems. Nat Rev Microbiol 1: 137149.
  • Chevalier N, Moser M, Koch HG, Schimz KL, Willery E, Locht C, Jacob-Dubuisson F & Müller M (2004) Membrane targeting of a bacterial virulence factor harbouring an extended signal peptide. J Mol Microbiol Biotechnol 8: 718.
  • Chintalacharuvu KR, Chuang PD, Dragoman A, Fernandez CZ, Qiu J, Plaut AG, Trinh KR, Gala FA & Morrison SL (2003) Cleavage of the human immunoglobulin A1 (IgA1) hinge region by IgA1 proteases requires structures in the Fc region of IgA. Infect Immun 71: 25632570.
  • Christie PJ (2001) Type IV secretion: intercellular transfer of macromolecules by systems ancestrally related to conjugation machines. Mol Microbiol 40: 294305.
  • Christie PJ (2004) Type IV secretion: the Agrobacterium VirB/D4 system and related conjugation systems. Biochim Biophys Acta 1694: 219234.
  • Clantin B, Hodak H, Willery E, Locht C, Jacob-Dubuisson F & Villeret V (2004) The crystal structure of filamentous hemagglutinin secretion domain and its implications for the two-partner secretion pathway. Proc Natl Acad Sci USA 101: 61946199.
  • Comanducci M, Bambini S, Brunelli B, et al. (2002) NadA, a novel vaccine candidate of Neisseria meningitidis. J Exp Med 195: 14451454.
  • Comanducci M, Bambini S, Caugant DA, Mora M, Brunelli B, Capecchi B, Ciucchi L, Rappuoli R & Pizza M (2004) NadA diversity and carriage in Neisseria meningitidis. Infect Immun 72: 42174223.
  • Coutte L, Antoine R, Drobecq H, Locht C & Jacob-Dubuisson F (2001) Subtilisin-like autotransporter serves as maturation protease in a bacterial secretion pathway. EMBO J 20: 50405048.
  • Coutte L, Alonso S, Reveneau N, Willery E, Quatannens B, Locht C & Jacob-Dubuisson F (2003a) Role of adhesin release for mucosal colonization by a bacterial pathogen. J Exp Med 197: 735742.
  • Coutte L, Willery E, Antoine R, Drobecq H, Locht C & Jacob-Dubuisson F (2003b) Surface anchoring of bacterial subtilisin important for maturation function. Mol Microbiol 49: 529539.
  • Darville T (1999) Gonorrhea. Pediatr Rev 20: 125128.
  • Davis J, Smith AL, Hughes WR & Golomb M (2001) Evolution of an autotransporter: domain shuffling and lateral transfer from pathogenic Haemophilus to Neisseria. J Bacteriol 183: 46264635.
  • Delepelaire P (1994) PrtD, the integral membrane ATP-binding cassette component of the Erwinia chrysanthemi metalloprotease secretion system, exhibits a secretion signal-regulated ATPase activity. J Biol Chem 269: 2795227957.
  • Delepelaire P (2004) Type I secretion in Gram-negative bacteria. Biochim Biophys Acta 1694: 149161.
  • Desplats C & Krisch HM (2003) The diversity and evolution of the T4-type bacteriophages. Res Microbiol 154: 259267.
  • van Deuren M, Brandtzaeg P & van der Meer JW (2000) Update on meningococcal disease with emphasis on pathogenesis and clinical management. Clin Microbiol Rev 13: 144166.
  • Dillard JP & Seifert HS (2001) A variable genetic island specific for Neisseria gonorrhoeae is involved in providing DNA for natural transformation and is found more often in disseminated infection isolates. Mol Microbiol 41: 263277.
  • Dinh T, Paulsen IT & Saier Jr MH (1994) A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of Gram-negative bacteria. J Bacteriol 176: 38253831.
  • Duong F, Lazdunski A & Murgier M (1996) Protein secretion by heterologous bacterial ABC-transporters: the C-terminus secretion signal of the secreted protein confers high recognition specificity. Mol Microbiol 21: 459470.
  • Dutta PR, Cappello R, Navarro-Garcia F & Nataro JP (2002) Functional comparison of serine protease autotransporters of Enterobacteriaceae. Infect Immun 70: 71057113.
  • Edwards JL & Apicella MA (2004) The molecular mechanisms used by Neisseria gonorrhoeae to initiate infection differ between men and women. Clin Microbiol Rev 17: 965981.
  • Egile C, D'Hauteville H, Parsot C & Sansonetti PJ (1997) SopA, the outer membrane protease responsible for polar localization of IcsA in Shigella flexneri. Mol Microbiol 23: 10631073.
  • Emonts M, Hazelzet JA, de Groot R & Hermans PW (2003) Host genetic determinants of Neisseria meningitidis infections. Lancet Infect Dis 3: 565577.
  • Emsley P, Charles IG, Fairweather NF & Isaacs NW (1996) Structure of Bordetella pertussis virulence factor P.69 pertactin. Nature 381: 9092.
  • Farizo KM, Huang T & Burns DL (2000) Importance of holotoxin assembly in Ptl-mediated secretion of pertussis toxin from Bordetella pertussis. Infect Immun 68: 40494054.
  • Fink DL, Cope LD, Hansen EJ & St.Geme III JW (2001) The Hemophilus influenzae Hap autotransporter is a chymotrypsin clan serine protease and undergoes autoproteolysis via an intermolecular mechanism. J Biol Chem 276: 3949239500.
  • Fink DL, Buscher AZ, Green B, Fernsten P & St.Geme III JW (2002) The Haemophilus influenzae Hap autotransporter mediates microcolony formation and adherence to epithelial cells and extracellular matrix via binding regions in the C-terminal end of the passenger domain. Cell Microbiol 5: 175186.
  • Fink DL & St.Geme III JW (2003) Chromosomal expression of the Haemophilus influenzae Hap autotransporter allows fine-tuned regulation of adhesive potential via inhibition of intermolecular autoproteolysis. J Bacteriol 185: 16081615.
  • Finlay BB & Falkow S (1997) Common themes in microbial pathogenicity revisited. Microbiol Mol Biol Rev 61: 136169.
  • Forman S, Linhartova I, Osic̆ka R, Nassif X, Šebo P & Pelicic V (2003) Neisseria meningitidis RTX proteins are not required for virulence in infant rats. Infect Immun 71: 22532257.
  • Fralick JA (1996) Evidence that TolC is required for functioning of the Mar/AcrAB efflux pump of Escherichia coli. J Bacteriol 178: 58035805.
  • Fukasawa LO, Gorla MC, Lemos AP, Schenkman RP, Brandileone MC, Fox JW, Raw I, Frasch CE & Tanizaki MM (2003) Immune response to native NadA from Neisseria meningitidis and its expression in clinical isolates in Brazil. J Med Microbiol 52: 121125.
  • Gilson L, Mahanty HK & Kolter R (1990) Genetic analysis of an MDR-like export system: the secretion of colicin V. EMBO J 9: 38753884.
  • Goebel W & Hedgpeth J (1982) Cloning and functional characterization of the plasmid-encoded hemolysin determinant of Escherichia coli. J Bacteriol 151: 12901298.
  • Gold R, Goldschneider I, Lepow ML, Draper TF & Randolph M (1978) Carriage of Neisseria meningitidis and Neisseria lactamica in infants and children. J Infect Dis 137: 112121.
  • Grass S, Buscher AZ, Swords WE, Apicella MA, Barenkamp SJ, Ozchlewski N & St.Geme III JW (2003) The Haemophilus influenzae HMW1 adhesin is glycosylated in a process that requires HMW1C and phosphoglucomutase, an enzyme involved in lipooligosaccharide biosynthesis. Mol Microbiol 48: 737751.
  • Guédin S, Willery E, Tommassen J, Fort E, Drobecq H, Locht C & Jacob-Dubuisson F (2001) Novel topological features of FhaC, the outer membrane transporter involved in the secretion of the Bordetella pertussis filamentous hemagglutinin. J Biol Chem 275: 3020230210.
  • Haas R & Meyer TF (1986) The repertoire of silent pilus genes in Neisseria gonorrhoeae: evidence for gene conversion. Cell 44: 107115.
  • Hamilton HL, Dominguez NM, Schwartz KJ, Hackett KT & Dillard JP (2005) Neisseria gonorrhoeae secretes chromosomal DNA via a novel type IV secretion system. Mol Microbiol 55: 17041721.
  • Hauck CR & Meyer TF (1997) The lysosomal/phagosomal membrane protein h-lamp-1 is a target of the IgA1 protease of Neisseria gonorrhoeae. FEBS Lett 405: 8690.
  • Henderson IR & Nataro JP (2001) Virulence functions of autotransporter proteins. Infect Immun 69: 12311243.
  • Henderson IR, Navarro-Garcia F & Nataro JP (1998) The great escape: structure and function of the autotransporter proteins. Trends Microbiol 6: 370378.
  • Henderson IR, Cappello R & Nataro JP (2000) Autotransporter proteins, evolution and redefining protein secretion. Trends Microbiol 8: 529532.
  • Hendrixson DR & St. Geme III JW (1998) The Haemophilus influenzae Hap serine protease promotes adherence and microcolony formation, potentiated by a soluble host protein. Mol Cell 2: 841850.
  • Hinsa SM, Espinosa-Urgel M, Ramos JL & O'Toole GA (2003) Transition from reversible to irreversible attachment during biofilm formation by Pseudomonas fluorescens WCS365 requires an ABC transporter and a large secreted protein. Mol Microbiol 49: 905918.
  • Hoiczyk E, Roggenkamp A, Reichenbecher M, Lupas A & Heesemann J (2000) Structure and sequence analysis of Yersinia YadA and Moraxella UspAs reveal a novel class of adhesins. EMBO J 19: 59895999.
  • Hopper S, Vasquez B, Merz A, Clary S, Wilbur JS & So M (2000) Effects of the immunoglobulin A1 protease on Neisseria gonorrhoeae trafficking across polarized T84 epithelial monolayers. Infect Immun 68: 906911.
  • Horstman AL & Kuehn MJ (2000) Enterotoxigenic Escherichia coli secretes active heat-labile enterotoxin via outer membrane vesicles. J Biol Chem 275: 1248912496.
  • Hughes C, Stanley P & Koronakis V (1992) E. coli hemolysin interactions with prokaryotic and eukaryotic cell membranes. Bioessays 14: 519525.
  • Humphries HE, Triantafilou M, Makepeace BL, Heckels JE, Triantafilou K & Christodoulides M (2005) Activation of human meningeal cells is modulated by lipopolysaccharide (LPS) and non-LPS components of Neisseria meningitidis and is independent of Toll-like receptor (TLR)4 and TLR2 signalling. Cell Microbiol 7: 415430.
  • Jacob-Dubuisson F, Buisine C, Willery E, Renauld-Mongénie G & Locht C (1997) Lack of functional complementation between Bordetella pertussis filamentous hemagglutinin and Proteus mirabilis HpmA hemolysin secretion machineries. J Bacteriol 179: 775783.
  • Jacob-Dubuisson F, El-Hamel C, Saint N, Guédin S, Willery E, Molle G & Locht C (1999) Channel formation by FhaC, the outer membrane protein involved in the secretion of the Bordetella pertussis filamentous hemagglutinin. J Biol Chem 274: 3773137735.
  • Jacob-Dubuisson F, Antoine R & Locht C (2000) Autotransporter proteins, evolution and redefining protein secretion: response. Trends Microbiol 8: 533534.
  • Jacob-Dubuisson F, Locht C & Antoine R (2001) Two-partner secretion in Gram-negative bacteria: a thrifty, specific pathway for large virulence proteins. Mol Microbiol 40: 306313.
  • Jacob-Dubuisson F, Fernandez R & Coutte L (2004) Protein secretion through autotransporter and two-partner pathways. Biochim Biophys Acta 1694: 235257.
  • Jose J, Wölk U, Lorenzen D, Wenschuh H & Meyer TF (2000) Human T-cell response to meningococcal immunoglobulin A1 protease associated alpha-proteins. Scand J Immunol 51: 176185.
  • Jose J, Otto GW & Meyer TF (2003) The integration site of the iga gene in commensal Neisseria sp. Mol Genet Genomics 269: 197204.
  • Kajava AV, Cheng N, Cleaver R, Kessel M, Simon MN, Willery E, Jacob-Dubuisson F, Locht C & Steven AC (2001) Beta-helix model for the filamentous haemagglutinin adhesin of Bordetella pertussis and related bacterial secretory proteins. Mol Microbiol 42: 279292.
  • de Keyzer J, van der Does C & Driessen AJ (2003) The bacterial translocase: a dynamic protein channel complex. Cell Mol Life Sci 60: 20342052.
  • Klauser T, Pohlner J & Meyer TF (1990) Extracellular transport of cholera toxin B subunit using Neisseria IgA protease β-domain: conformation-dependent outer membrane translocation. EMBO J 9: 19911999.
  • Klauser T, Pohlner J & Meyer TF (1992) Selective extracellular release of cholera toxin B subunit by Escherichia coli: dissection of Neisseria Igaβ-mediated outer membrane transport. EMBO J 11: 23272335.
  • Klauser T, Krämer J, Otzelberger K, Pohlner J & Meyer TF (1993) Characterization of the Neisseria Igaβ-core. The essential unit for outer membrane targeting and extracellular protein secretion. J Mol Biol 234: 579593.
  • Klee SR, Nassif X, Kusecek B, Merker P, Beretti JL, Achtman M & Tinsley CR (2000) Molecular and biological analysis of eight genetic islands that distinguish Neisseria meningitidis from the closely related pathogen Neisseria gonorrhoeae. Infect Immun 68: 20822095.
  • Kline KA, Sechman EV, Skaar EP & Seifert HS (2003) Recombination, repair and replication in the pathogenic Neisseriae: the 3 R's of molecular genetics of two human-specific bacterial pathogens. Mol Microbiol 50: 313.
  • Koronakis V, Hughes C & Koronakis E (1993) ATPase activity and ATP/ADP-induced conformational change in the soluble domain of the bacterial protein translocator HlyB. Mol Microbiol 8: 11631175.
  • Koronakis V, Sharff A, Koronakis E, Luisi B & Hughes C (2000) Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export. Nature 405: 914919.
  • Könninger UW, Hobbie S, Benz R & Braun V (1999) The haemolysin-secreting ShlB protein of the outer membrane of Serratia marcescens: determination of surface-exposed residues and formation of ion-permeable pores by ShlB mutants in artificial lipid bilayer membranes. Mol Microbiol 32: 12121225.
  • Lee VT & Schneewind O (2001) Protein secretion and the pathogenesis of bacterial infections. Genes Dev 15: 17251752.
  • Leininger E, Roberts M, Kenimer JG, Charles IG, Fairweather N, Novotny P & Brennan MJ (1991) Pertactin, an Arg-Gly-Asp-containing Bordetella pertussis surface protein that promotes adherence of mammalian cells. Proc Natl Acad Sci USA 88: 345349.
  • Li LJ, Dougan G, Novotny P & Charles IG (1991) P.70 pertactin, an outer-membrane protein from Bordetella parapertussis: cloning, nucleotide sequence and surface expression in Escherichia coli. Mol Microbiol 5: 409417.
  • Lin L, Ayala P, Larson J, Mulks M, Fukuda M, Carlsson SR, Enns C & So M (1997) The Neisseria type 2 IgA1 protease cleaves LAMP1 and promotes survival of bacteria within epithelial cells. Mol Microbiol 24: 10831094.
  • Litt DJ, Savino S, Beddek A, et al. (2004) Putative vaccine antigens from Neisseria meningitidis recognized by serum antibodies of young children convalescing after meningococcal disease. J Infect Dis 190: 14881497.
  • Lomholt H, Poulsen K, Caugant DA & Kilian M (1992) Molecular polymorphism and epidemiology of Neisseria meningitidis immunoglobulin A1 proteases. Proc Natl Acad Sci USA 89: 21202124.
  • Lomholt H, Poulsen K & Kilian M (1995) Comparative characterization of the iga gene encoding IgA1 protease in Neisseria meningitidis, Neisseria gonorrhoeae and Haemophilus influenzae. Mol Microbiol 15: 495506.
  • Lorenzen DR, Düx F, Wölk U, Tsirpouchtsidis A, Haas G & Meyer TF (1999) Immunoglobulin A1 protease, an exoenzyme of pathogenic Neisseriae, is a potent inducer of proinflammatory cytokines. J Exp Med 190: 10491058.
  • Loveless BJ & Saier Jr MH (1997) A novel family of channel-forming, autotransporting, bacterial virulence factors. Mol Membr Biol 14: 113123.
  • Létoffé S, Delepelaire P & Wandersman C (1996) Protein secretion in gram-negative bacteria: assembly of the three components of ABC protein-mediated exporters is ordered and promoted by substrate binding. EMBO J 15: 58045811.
  • Makhov AM, Hannah JH, Brennan MJ, Trus BL, Kocsis E, Conway JF, Wingfield PT, Simon MN & Steven AC (1994) Filamentous hemagglutinin of Bordetella pertussis. A bacterial adhesin formed as a 50-nm monomeric rigid rod based on a 19-residue repeat motif rich in beta strands and turns. J Mol Biol 241: 110124.
  • Mansa B & Kilian M (1986) Retained antigen-binding activity of Fabα fragments of human monoclonal immunoglobulin A1 (IgA1) cleaved by IgA1 protease. Infect Immun 52: 171174.
  • Martin P, van de Ven T, Mouchel N, Jeffries AC, Hood DW & Moxon ER (2003) Experimentally revised repertoire of putative contingency loci in Neisseria meningitidis strain MC58: evidence for a novel mechanism of phase variation. Mol Microbiol 50: 245257.
  • Massari P, Ho Y & Wetzler LM (2000) Neisseria meningitidis porin PorB interacts with mitochondria and protects cells from apoptosis. Proc Natl Acad Sci USA 97: 90709075.
  • Massari P, King CA, Ho AY & Wetzler LM (2003) Neisserial PorB is translocated to the mitochondria of HeLa cells infected with Neisseria meningitidis and protects cells from apoptosis. Cell Microbiol 2003 5: 99109.
  • Mehr IJ & Seifert HS (1998) Differential roles of homologous recombination pathways in Neisseria gonorrhoeae pilin antigenic variation, DNA transformation and DNA repair. Mol Microbiol 30: 697710.
  • Meyer TF (1999) Pathogenic Neisseriae: complexity of pathogen-host cell interplay. Clin Infect Dis 28: 433441.
  • Mirlashari MR, Hagberg IA & Lyberg T (2002) Platelet-platelet and platelet-leukocyte interactions induced by outer membrane vesicles from N. meningitidis. Platelets 13: 9199.
  • Muenzner P, Naumann M, Meyer TF & Gray-Owen SD (2001) Pathogenic Neisseria trigger expression of their carcinoembryonic antigen-related cellular adhesion molecule 1 (CEACAM1; previously CD66a) receptor on primary endothelial cells by activating the immediate early response transcription factor, nuclear factor-kappaB. J Biol Chem 276: 2433124340.
  • Mulks MH, Plaut AG, Feldman HA & Frangione B (1980) IgA proteases of two distinct specificities are released by Neisseria meningitidis. J Exp Med 152: 14421447.
  • Müller A, Günther D, Brinkmann V, Hurwitz R, Meyer TF & Rudel T (2000) Targeting of the pro-apoptotic VDAC-like porin (PorB) of Neisseria gonorrhoeae to mitochondria of infected cells. EMBO J 19: 53325343.
  • Müller D, Benz I, Tapadar D, Buddenborg C, Greune L & Schmidt MA (2005) Arrangement of the translocator of the autotransporter adhesin involved in diffuse adherence on the bacterial surface. Infect Immun 73: 38513859.
  • Nummelin H, Merckel MC, Leo JC, Lankinen H, Skurnik M & Goldman A (2004) The Yersinia adhesin YadA collagen-binding domain structure is a novel left-handed parallel beta-roll. EMBO J 23: 701711.
  • Odenbreit S, Till M, Hofreuter D, Faller G & Haas R (1999) Genetic and functional characterization of the alpAB gene locus essential for the adhesion of Helicobacter pylori to human gastric tissue. Mol Microbiol 31: 15371548.
  • Odenbreit S, Puls J, Sedlmaier B, Gerland E, Fischer W & Haas R (2000) Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion. Science 287: 14971500.
  • Oomen CJ, van Ulsen P, Van Gelder P, Feijen M, Tommassen J & Gros P (2004) Structure of the translocator domain of a bacterial autotransporter. EMBO J 23: 12571266.
  • Osic̆ka R, Kalmusová J, Kŕíz̆ová P & S̆ebo P (2001) Neisseria meningitidis RTX protein FrpC induces high levels of serum antibodies during invasive disease: polymorphism of frpC alleles and purification of recombinant FrpC. Infect Immun 69: 55095519.
  • Osic̆ka R, Procházková K, Šulc M, Linhartová I, Havlíc̆ek V & S̆ebo P (2004) A novel “clip-and-link” activity of repeat in toxin (RTX) proteins from Gram-negative pathogens. Covalent protein cross-linking by an Asp-Lys isopeptide bond upon calcium-dependent processing at an Asp-Pro bond. J Biol Chem 279: 2494424956.
  • Otto BR, van Dooren SJ, Nuijens JH, Luirink J & Oudega B (1998) Characterization of a hemoglobin protease secreted by the pathogenic Escherichia coli strain EB1. J Exp Med 188: 10911103.
  • Otto BR, Sijbrandi R, Luirink J, Oudega B, Heddle JG, Mizutani K, Park SY & Tame JR (2005) Crystal structure of hemoglobin protease, a heme binding autotransporter protein from pathogenic Escherichia coli. J Biol Chem 280: 1733917345.
  • Parkhill J, Achtman M, James KD, et al. (2000) Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491. Nature 404: 502506.
  • Peak IR, Jennings MP, Hood DW & Moxon ER (1999) Tetranucleotide repeats identify novel virulence determinant homologues in Neisseria meningitidis. Microb Pathog 26: 1323.
  • Peak IR, Srikhanta Y, Dieckelmann M, Moxon ER & Jennings MP (2000) Identification and characterisation of a novel conserved outer membrane protein from Neisseria meningitidis. FEMS Immunol Med Microbiol 28: 329334.
  • Peltola H (1983) Meningococcal disease: still with us. Rev Infect Dis 5: 7191.
  • Peltola H (1998) Meningococcal vaccines. Current status and future possibilities. Drugs 55: 347366.
  • Petitt RK & Judd RC (1992) Characterization of naturally elaborated blebs from serum-susceptible and serum-resistant strains of Neisseria gonorrhoeae. Mol Microbiol 6: 723728.
  • Pimenta AL, Young J, Holland IB & Blight MA (1999) Antibody analysis of the localisation, expression and stability of HlyD, the MFP component of the E. coli haemolysin translocator. Mol Gen Genet 261: 122132.
  • Pizza M, Scarlato V, Masignani V, et al. (2000) Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing. Science 287: 18161820.
  • Plaut AG, Gilbert JV, Artenstein MS & Capra JD (1975) Neisseria gonorrhoeae and Neisseria meningitidis: extracellular enzyme cleaves human immunoglobulin A. Science 190: 11031105.
  • Pohlner J, Halter R, Beyreuther K & Meyer TF (1987) Gene structure and extracellular secretion of Neisseria gonorrhoeae IgA protease. Nature 325: 458462.
  • Pohlner J, Langenberg U, Wölk U, Beck SC & Meyer TF (1995) Uptake and nuclear transport of Neisseria IgA1 protease-associated alpha-proteins in human cells. Mol Microbiol 17: 10731083.
  • Popp A, Billker O & Rudel T (2001) Signal transduction pathways induced by virulence factors of Neisseria gonorrhoeae. Int J Med Microbiol 291: 307314.
  • Post D, Zhang D, Eastvold JS, Teghanemt A, Gibson BW & Weiss JP (2005) Biochemical and functional characterization of membrane blebs purified from Neisseria meningitidis serogroup B. J Biol Chem 280: 3838338394.
  • Prochazkova K, Osicka R, Linhartova I, Halada P, Sulc M & Sebo P (2005) The Neisseria meningitidis outer membrane lipoprotein FrpD binds the RTX protein FrpC. J Biol Chem 280: 32513258.
  • Ramsay ME, Andrews N, Kaczmarski EB & Miller E (2001) Efficacy of meningococcal serogroup C conjugate vaccine in teenagers and toddlers in England. Lancet 357: 195196.
  • Robinson C & Bolhuis A (2004) Tat-dependent protein targeting in prokaryotes and chloroplasts. Biochim Biophys Acta 1694: 135147.
  • Robinson K, Taraktsoglou M, Rowe KS, Wooldridge KG & Ala'Aldeen DA (2004) Secreted proteins from Neisseria meningitidis mediate differential human gene expression and immune activation. Cell Microbiol 6: 927938.
  • Roggenkamp A, Ackermann N, Jacobi CA, Truelzsch K, Hoffmann H & Heesemann J (2003) Molecular analysis of transport and oligomerization of the Yersinia enterocolitica adhesin YadA. J Bacteriol 185: 37353744.
  • Saunders NJ, Jeffries AC, Peden JF, Hood DW, Tettelin H, Rappuoli R & Moxon ER (2000) Repeat-associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58. Mol Microbiol 37: 207215.
  • Schönherr R, Tsolis R, Focareta T & Braun V (1993) Amino acid replacements in the Serratia marcescens haemolysin ShlA define sites involved in activation and secretion. Mol Microbiol 9: 12291237.
  • Seib KL, Tseng HJ, McEwan AG, Apicella MA & Jennings MP (2004) Defenses against oxidative stress in Neisseria gonorrhoeae and Neisseria meningitidis: distinctive systems for different lifestyles. J Infect Dis 190: 136147.
  • Senior BW, Stewart WW, Galloway C & Kerr MA (2001) Cleavage of the hormone human chorionic gonadotropin, by the Type 1 IgA1 protease of Neisseria gonorrhoeae, and its implications. J Infect Dis 184: 922925.
  • Senior BW & Woof JM (2005) Effect of mutations in the human immunoglobulin A1 (IgA1) hinge on its susceptibility to cleavage by diverse bacterial IgA1 proteases. Infect Immun 73: 15151522.
  • Serruto D, Adu-Bobie J, Scarselli M, Veggi D, Pizza M, Rappuoli R & Aricò B (2003) Neisseria meningitidis App, a new adhesin with autocatalytic serine protease activity. Mol Microbiol 48: 323334.
  • Sijbrandi R, Urbanus ML, Ten Hagen-Jongman CM, Bernstein HD, Oudega B, Otto BR & Luirink J (2003) Signal recognition particle (SRP)-mediated targeting and Sec-dependent translocation of an extracellular Escherichia coli protein. J Biol Chem 278: 46544659.
  • St.Geme III JW & Cutter D (2000) The Haemophilus influenzae Hia adhesin is an autotransporter protein that remains uncleaved at the C terminus and fully cell associated. J Bacteriol 182: 60056013.
  • St.Geme III JW, de la Morena ML & Falkow S (1994) A Haemophilus influenzae IgA protease-like protein promotes intimate interaction with human epithelial cells. Mol Microbiol 14: 217233.
  • St.Geme III JW, Cutter D & Barenkamp SJ (1996) Characterization of the genetic locus encoding Haemophilus influenzae type b surface fibrils. J Bacteriol 178: 62816287.
  • Stathopoulos C, Provence DL & Curtiss III R (1999) Characterization of the avian pathogenic Escherichia coli hemagglutinin Tsh, a member of the immunoglobulin A protease-type family of autotransporters. Infect Immun 67: 772781.
  • Suhr M, Benz I & Schmidt MA (1996) Processing of the AIDA-I precursor: removal of AIDAc and evidence for the outer membrane anchoring as a beta-barrel structure. Mol Microbiol 22: 3142.
  • Surana NK, Cutter D, Barenkamp SJ & St.Geme III JW (2004a) The Haemophilus influenzae Hia autotransporter contains an unusually short trimeric translocator domain. J Biol Chem 279: 1467914685.
  • Surana NK, Grass S, Hardy GG, Li H, Thanassi DG & St.Geme III JW (2004b) Evidence for conservation of architecture and physical properties of Omp85-like proteins throughout evolution. Proc Natl Acad Sci USA 101: 1449714502.
  • Szabady RL, Peterson JH, Skillman KM & Bernstein HD (2005) An unusual signal peptide facilitates late steps in the biogenesis of a bacterial autotransporter. Proc Natl Acad Sci USA 102: 221226.
  • Taha MK (2000) Neisseria meningitidis induces the expression of the TNF-alpha gene in endothelial cells. Cytokine 12: 2125.
  • Taha MK, Deghmane AE, Antignac A, Zarantonelli ML, Larribe M & Alonso JM (2002) The duality of virulence and transmissibility in Neisseria meningitidis. Trends Microbiol 10: 376382.
  • Tettelin H, Saunders NJ, Heidelberg J, et al. (2000) Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. Science 287: 18091815.
  • Thanabalu T, Koronakis E, Hughes C & Koronakis V (1998) Substrate-induced assembly of a contiguous channel for protein export from E. coli: reversible bridging of an inner-membrane translocase to an outer membrane exit pore. EMBO J 17: 64876496.
  • Thompson SA & Sparling PF (1993) The RTX cytotoxin-related FrpA protein of Neisseria meningitidis is secreted extracellularly by meningococci and by HlyBD+Escherichia coli. Infect Immun 61: 29062911.
  • Thompson SA, Wang LL, West A & Sparling PF (1993a) Neisseria meningitidis produces iron-regulated proteins related to the RTX family of exoproteins. J Bacteriol 175: 811818.
  • Thompson SA, Wang LL & Sparling PF (1993b) Cloning and nucleotide sequence of frpC, a second gene from Neisseria meningitidis encoding a protein similar to RTX cytotoxins. Mol Microbiol 9: 8596.
  • Tinsley CR & Nassif X (1996) Analysis of the genetic differences between Neisseria meningitidis and Neisseria gonorrhoeae: two closely related bacteria expressing two different pathogenicities. Proc Natl Acad Sci USA 93: 1110911114.
  • Turner DP, Wooldridge KG & Ala'Aldeen DA (2002) Autotransported serine protease A of Neisseria meningitidis: an immunogenic, surface-exposed outer membrane, and secreted protein. Infect Immun 70: 44474461.
  • Tzeng YL & Stevens DS (2000) Epidemiology and pathogenesis of Neisseria meningitidis. Microbes Infect 2: 687700.
  • van Ulsen P, van Alphen L, Hopman CT, van der Ende A & Tommassen J (2001) In vivo expression of Neisseria meningitidis proteins homologous to the Haemophilus influenzae Hap and Hia autotransporters. FEMS Immunol Med Microbiol 32: 5364.
  • van Ulsen P, van Alphen L, Ten Hove J, Fransen F, van der Ley P & Tommassen J (2003) A Neisserial autotransporter NalP modulating the processing of other autotransporters. Mol Microbiol 50: 10171030.
  • Veiga E, de Lorenzo V & Fernandez LA (1999) Probing secretion and translocation of a β-autotransporter using a reporter single-chain Fv as a cognate passenger domain. Mol Microbiol 33: 12321243.
  • Veiga E, Sugawara E, Nikaido H, de Lorenzo V & Fernandez LA (2002) Export of autotransported proteins proceeds through an oligomeric ring shaped by C-terminal domains. EMBO J 21: 21222131.
  • Veiga E, de Lorenzo V & Fernandez LA (2004) Structural tolerance of bacterial autotransporters for folded passenger protein domains. Mol Microbiol 52: 10691080.
  • Vermont CL & van den Dobbelsteen GP (2003) Meningococcal serogroup B infections: a search for a broadly protective vaccine. Expert Rev Vaccines 2: 673681.
  • Vitovski S, Read RC & Sayers JR (1999) Invasive isolates of Neisseria meningitidis possess enhanced immunoglobulin A1 protease activity compared to colonizing strains. FASEB J 13: 331337.
  • Vogel U, Claus H & Frosch M (2004) Genetic lineages and their traits in Neisseria meningitidis. Int J Med Microbiol 294: 7582.
  • Voulhoux R, Bos MP, Geurtsen J, Mols M & Tommassen J (2003) Role of a highly conserved bacterial protein in outer membrane protein assembly. Science 299: 262265.
  • Wai S, Lindmark B, Söderblom T, Takade A, Westermark M, Oscarsson J, Jass J, Richter-Dahlfors A, Mizunoe Y & Uhlin B (2003) Vesicle-mediated export and assembly of pore-forming oligomers of the enterobacterial ClyA cytotoxin. Cell 115: 2535.
  • Walker G, Hertle R & Braun V (2004) Activation of Serratia marcescens hemolysin through a conformational change. Infect Immun 72: 611614.
  • Wetzler LM, Blake MS, Barry K & Gotschlich EC (1992) Gonococcal porin vaccine evaluation: comparison of Por proteosomes, liposomes, and blebs isolated from rmp deletion mutants. J Infect Dis 166: 551555.
  • Yazdankhah SP & Caugant DA (2004) Neisseria meningitidis: an overview of the carriage state. J Med Microbiol 53: 821832.
  • Yen MR, Peabody CR, Partovi SM, Zhai Y, Tseng YH & Saier Jr MH (2002) Protein-translocating outer membrane porins of Gram-negative bacteria. Biochim Biophys Acta 1562: 631.
  • Yeo HJ, Cotter SE, Laarmann S, Juehne T, St.Geme III JW & Waksman G (2004) Structural basis for host recognition by the Haemophilus influenzae Hia autotransporter. EMBO J 23: 12451256.
  • Young J & Holland IB (1999) ABC transporters: bacterial exporters – revisited five years on. Biochim Biophys Acta 1461: 177200.
  • Zhang F, Sheps JA & Ling V (1993) Complementation of transport-deficient mutants of Escherichia coliα-hemolysin by second-site mutations in the transporter hemolysin B. J Biol Chem 268: 1988919895.