• 1
    Munaron L, Antoniotti S, Lovisolo D. Intracellular calcium signals and control of cell proliferation: how many mechanisms? J Cell Mol Med. 2004; 8: 1618.
  • 2
    Christakos S, Gabrielides C, Rhoten WB. Vitamin D-dependent calcium binding proteins: chemistry, distribution, functional considerations, and molecular biology. Endocr Rev. 1989; 10: 326.
  • 3
    Jeung EB, Krisinger J, Dann JL, Leung PC. Molecular cloning of the full-length cDNA encoding the human calbindin-D9k. FEBS Lett. 1992; 307: 2248.
  • 4
    Jeung EB, Leung PC, Krisinger J. The human cal-bindin-D9k ene. Complete structure and implications on steroid hormone regulation. J Mol Biol. 1994; 235: 12318.
  • 5
    Armbrecht HJ, Boltz M, Strong R, Richardson A, Bruns ME, Christakos S. Expression of calbindin-D decreases with age in intestine and kidney. Endocrinology. 1989; 125: 29506.
  • 6
    Mathieu CL, Burnett SH, Mills SE, Overpeck JG, Bruns DE, Bruns ME. Gestational changes in cal-bindin-D9k in rat uterus, yolk sac, and placenta:impli-cations for maternal-fetal calcium transport and uterine muscle function. Proc Natl Acad Sci USA. 1989; 86:34337.
  • 7
    Mathieu CL, Mills SE, Burnett SH, Cloney DL, Bruns DE, Bruns ME. The presence and estrogen control of immunoreactive calbindin-D9k in the fallopian tube of the rat. Endocrinology. 1989; 125: 274550.
  • 8
    Seifert MF, Gray RW, Bruns ME. Elevated levels of vitamin D-dependent calcium-binding protein (cal-bindin-D9k) in the osteosclerotic (oc) mouse. Endocrinology. 1988; 122: 106773.
  • 9
    Darwish HM, DeLuca HF. Identification of a 1,25-dihydroxyvitamin D3-response element in the 5′-flanking region of the rat calbindin D-9k gene. Proc Natl Acad Sci USA. 1992; 89: 6037.
  • 10
    Wasserman RH, Fullmer CS. On the molecular mechanism of intestinal calcium transport. Adv Exp Med Biol. 1989; 249: 4565.
  • 11
    Krisinger J, Strom M, Darwish HD, Perlman K, Smith C, DeLuca HF. Induction of calbindin-D 9k mRNA but not calcium transport in rat intestine by 1,25-dihydroxyvitamin D3 24-homologs. J Biol Chem. 1991; 266: 19103.
  • 12
    An BS, Choi KC, Kang SK, Hwang WS, Jeung EB. Novel Calbindin-D9k protein as a useful biomarker for environmental estrogenic compounds in the uterus of immature rats. Reprod Toxicol. 2003; 17: 3119.
  • 13
    Choi KC, Jeung EB. The biomarker and endocrine disruptors in mammals. J Reprod Dev. 2003; 49: 33745.
  • 14
    Hong EJ, Choi KC, Jeung EB. Maternal-fetal transfer of endocrine disruptors in the induction of Calbindin-D9k mRNA and protein during pregnancy in rat model. Mol Cell Endocrinol. 2003; 212: 6372.
  • 15
    Hong EJ, Choi KC, Jeung EB. Induction of cal-bindin-D9k messenger RNA and protein by maternal exposure to alkylphenols during late pregnancy in maternal and neonatal uteri of rats. Biol Reprod. 2004; 71: 66975.
  • 16
    Hong EJ, Choi KC, Jung YW, Leung PC, Jeung EB. Transfer of maternally injected endocrine disruptors through breast milk during lactation induces neonatal Calbindin-D9k in the rat model. Reprod Toxicol. 2004; 18: 6618.
  • 17
    Hoenderop JG, Dardenne O,Van Abel M, Van Der Kemp AW, Van Os CH, St -Arnaud R, Bindels RJ. Modulation of renal Ca2+ transport protein genes by dietary Ca2+ and 1,25-dihydroxyvitamin D3 in 25-hydroxyvitamin D3–1alpha-hydroxylase knockout mice. Faseb J. 2002; 16: 1398406.
  • 18
    Zheng W, Xie Y, Li G, Kong J, Feng JQ, Li YC. Critical role of calbindin-D28k in calcium homeostasis revealed by mice lacking both vitamin D receptor and calbindin-D28k. J Biol Chem. 2004; 279: 5240613.
  • 19
    Van Cromphaut SJ, Dewerchin M, Hoenderop JG, Stockmans I, Van Herck E, Kato S, Bindels RJ, Collen D, Carmeliet P, Bouillon R, Carmeliet G. Duodenal calcium absorption in vitamin D receptor-knockout mice: functional and molecular aspects. Proc Natl Acad Sci USA. 2001; 98: 133249.
  • 20
    Lee GS, Lee KY, Choi KC, Ryu YH, Paik SG, Oh GT, Jeung EB. A Phenotype of a Calbindin-D9k Gene-Knockout is Compensated for by the Induction of Other Calcium-Transporter Genes in a Mouse Model. J Bone Miner Res. 2007; 22: 196878.
  • 21
    Xu J, Chang V, Joseph SB, Trujillo C, Bassilian S, Saad MF, Lee WN, Kurland IJ. Peroxisomal prolifer-ator-activated receptor alpha deficiency diminishes insulin-responsiveness of gluconeogenic/glycolytic/pentose gene expression and substrate cycle flux. Endocrinology. 2004;145:108795.
  • 22
    Tanabe M, Matsumoto T, Shibuya K, Tateda K, Miyazaki S, Nakane A, Iwakura Y, Yamaguchi K. Compensatory response of IL-1 gene knockout mice after pulmonary infection with Klebsiella pneumoni-ae. J Med Microbiol. 2005; 54: 713.
  • 23
    Wertheimer E, Spravchikov N, Trebicz M, Gartsbein M, Accili D, Avinoah I, Nofeh-Moses S, Sizyakov G, Tennenbaum T. The regulation of skin proliferation and differentiation in the IR null mouse: implications for skin complications of diabetes. Endocrinology. 2001; 142: 123441.
  • 24
    Brommage R. Measurement of calcium and phosphorus fluxes during lactation in the rat. J Nutr. 1989; 119: 42838.
  • 25
    Van Cromphaut SJ, Rummens K, Stockmans I, Van Herck E, Dijcks FA, Ederveen AG, Carmeliet P, Verhaeghe J, Bouillon R, Carmeliet G. Intestinal calcium transporter genes are upregulated by estrogens and the reproductive cycle through vitamin D receptor-independent mechanisms. J Bone Miner Res. 2003; 18: 172536.
  • 26
    Song Y, Peng X, Porta A, Takanaga H, Peng JB, Hediger MA, Fleet JC, Christakos S. Calcium transporter 1 and epithelial calcium channel messenger ribonucleic acid are differentially regulated by 1,25 dihydroxyvitamin D3 in the intestine and kidney of mice. Endocrinology. 2003; 144: 388594.
  • 27
    Brown AJ, Krits I, Armbrecht HJ. Effect of age, vitamin D, and calcium on the regulation of rat intestinal epithelial calcium channels. Arch Biochem Biophys. 2005; 437: 518.
  • 28
    Bruns ME, Kleeman E, Mills SE, Bruns DE, Herr JC. Immunochemical localization of vitamin D-dependent calcium-binding protein in mouse placenta and yolk sac. Anat Rec. 1985;213:5147, 32–5.
  • 29
    Delorme AC, Danan JL, Acker MG, Ripoche MA, Mathieu H. In rat uterus 17 beta-estradiol stimulates a calcium-binding protein similar to the duodenal vitamin D-dependent calcium-binding protein. Endocrinology. 1983; 113: 13407.
  • 30
    Warembourg M, Perret C, Thomasset M. Analysis and in situ detection of cholecalcin messenger RNA (9000 Mr CaBP) in the uterus of the pregnant rat. Cell Tissue Res. 1987; 247: 517.
  • 31
    Inpanbutr N, Miller EK, Petroff BK, Iacopino AM. CaBP9K levels during the luteal and follicular phases of the estrous cycle in the bovine uterus. Biol Reprod. 1994; 50: 56171.
  • 32
    L'Horset F, Blin C, Brehier A, Thomasset M, Perret C. Estrogen-induced calbindin-D 9k gene expression in the rat uterus during the estrous cycle:late antagonistic effect of progesterone. Endocrinology. 1993; 132: 48995.
  • 33
    L'Horset F, Perret C, Brehier A, Thomasset M. 17 beta-estradiol stimulates the calbindin-D9k (CaBP9k) gene expression at the transcriptional and posttran-scriptional levels in the rat uterus. Endocrinology. 1990; 127: 28917.
  • 34
    Krisinger J, Dann JL, Currie WD, Jeung EB, Leung PC. Calbindin-D9k mRNA is tightly regulated during the estrous cycle in the rat uterus. Mol Cell Endocrinol. 1992; 86: 11923.
  • 35
    An BS, Kang SK, Shin JH, Jeung EB. Stimulation of calbindin-D(9k) mRNA expression in the rat uterus by octyl-phenol, nonylphenol and bisphenol. Mol Cell Endocrinol. 2002; 191: 17786.
  • 36
    L'Horset F, Blin C, Colnot S, Lambert M, Thomasset M, Perret C. Calbindin-D9k gene expression in the uterus: study of the two messenger ribonucleic acid species and analysis of an imperfect estrogen-responsive element. Endocrinology. 1994; 134: 118.
  • 37
    Krisinger J, Setoyama T, Leung PC. Expression of calbindin-D9k in the early pregnant rat uterus:effects of RU 486 and correlation to estrogen receptor mRNA. Mol Cell Endocrinol. 1994; 102: 1522.
  • 38
    Krisinger J, Jeung EB, Simmen RC, Leung PC. Porcine calbindin-D9k gene:expression in endometrium, myometrium, and placenta in the absence of a functional estrogen response element in intron A. Biol Reprod. 1995;52:11523.
  • 39
    Yun SM, Choi KC, Kim IH, An BS, Lee GS, Hong EJ, Oh GT, Jeung EB. Dominant expression of porcine Calbindin-D9k in the uterus during a luteal phase. Mol Reprod Dev. 2004; 67: 2516.
  • 40
    Tatsumi K, Higuchi T, Fujiwara H, Nakayama T, Itoh K, Mori T, Fujii S, Fujita J. Expression of calcium binding protein D-9k messenger RNA in the mouse uterine endometrium during implantation. Mol Hum Reprod. 1999; 5: 15361.
  • 41
    Nie GY, Li Y, Wang J, Minoura H, Findlay JK, Salamonsen LA. Complex regulation of calcium-binding protein D9k (calbindin-D(9k)) in the mouse uterus during early pregnancy and at the site of embryo implantation. Biol Reprod. 2000; 62: 2736.
  • 42
    An BS, Choi KC, Kang SK, Lee GS, Hong EJ, Hwang WS, Jeung EB. Mouse calbindin-D(9k) gene expression in the uterus during late pregnancy and lactation. Mol Cell Endocrinol. 2003; 205: 7988.
  • 43
    Darwish H, Krisinger J, Furlow JD, Smith C, Murdoch FE, DeLuca HF. An estrogen-responsive element mediates the transcriptional regulation of calbindin D-9K gene in rat uterus. J Biol Chem. 1991; 266: 5518.
  • 44
    Krisinger J, Dann JL, Applegarth O, Currie WD, Jeung EB, Staun M, Leung PC. Calbindin-D9k gene expression during the perinatal period in the rat:cor-relation to estrogen receptor expression in uterus. Mol Cell Endocrinol. 1993; 97: 619.
  • 45
    Lee KY, Oh GT, Kang JH, Shin SM, Heo BE, Yun YW, Paik SG, Krisinger J, Leung PC, Jeung EB. Transcriptional regulation of the mouse calbindin-D9k gene by the ovarian sex hormone. Mol Cells. 2003;16:4853.
  • 46
    Belkacemi L, Gariepy G, Mounier C, Simoneau L, Lafond J. Calbindin-D9k (CaBP9k) localization and levels of expression in trophoblast cells from human term placenta. Cell Tissue Res. 2004; 315: 10717.
  • 47
    Jeung EB, Krisinger J, Dann JL, Leung PC. Cloning of the porcine Calbindin-D9k complementary deoxyribonucleic acid by anchored polymerase chain reaction technique. Biol Reprod. 1992;47:5038.
  • 48
    Jeung EB, Fan NC, Leung PC, Herr JC, Freemerman A, Krisinger J. The baboon expresses the calbindin-D9k gene in intestine but not in uterus and placenta:implication for conservation of the gene in primates. Mol Reprod Dev. 1995; 40: 4007.
  • 49
    Reiswig JD, Frazer GS, Inpanbutr N. Calbindin-D9k expression in the pregnant cow uterus and placenta. Histochem Cell Biol. 1995;104:16974.
  • 50
    Shamley DR, Veale G, Pettifor JM, Buffenstein R. Trophoblastic giant cells of the mouse placenta contain calbindin-D9k but not the vitamin D receptor. J Endocrinol. 1996; 150: 2532.
  • 51
    An BS, Choi K-C, Lee GS, Leung PC, Jeung E-B. Complex regulation of Calbindin-D9k in the mouse placenta and extra-embryonic membrane during mid- and late pregnancy. Mol Cell Endocrinol. 2004;214:3952.
  • 52
    Delorme AC, Danan JL, Mathieu H. Biochemical evidence for the presence of two vitamin D-dependent calcium-binding proteins in mouse kidney. J Biol Chem. 1983; 258: 187884.
  • 53
    Roche C, Bellaton C, Pansu D, Miller A 3rd, Bronner F. Localization of vitamin D-dependent active Ca2+ transport in rat duodenum and relation to CaBP. Am J Physiol. 1986; 251: G31420.
  • 54
    Walters JR, Howard A, Lowery LJ, Mawer EB, Legon S. Expression of genes involved in calcium absorption in human duodenum. Eur J Clin Invest. 1999; 29: 2149.
  • 55
    Kwiecinksi GG, Petrie GI, DeLuca HF. 1,25-Dihydroxyvitamin D3 restores fertility of vitamin D-deficient female rats. Am J Physiol. 1989; 256: E4837.
  • 56
    Uhland AM, Kwiecinski GG, DeLuca HF. Normalization of serum calcium restores fertility in vitamin D-deficient male rats. J Nutr. 1992; 122: 133844.
  • 57
    Lee GS, Choi KC, Park SM, An BS, Cho MC, Jeung EB. Expression of human Calbindin-D(9k) correlated with age, vitamin D receptor and blood calcium level in the gastrointestinal tissues. Clin Biochem. 2003; 36: 25561.
  • 58
    Kimberg DV, Baerg RD, Gershon E, Graudusius RT. Effect of cortisone treatment on the active transport of calcium by the small intestine. J Clin Invest. 1971; 50: 130921.
  • 59
    Shultz TD, Bollman S, Kumar R. Decreased intestinal calcium absorption in vivo and normal brush border membrane vesicle calcium uptake in cortisol-treated chickens:evidence for dissociation of calcium absorption from brush border vesicle uptake. Proc Natl Acad Sci USA. 1982; 79: 35426.
  • 60
    Feher JJ, Wasserman RH. Intestinal calcium-binding protein and calcium absorption in cortisol-treated chicks: effects of vitamin D3 and 1,25-dihydroxyvita-min D3. Endocrinology. 1979; 104: 54751.
  • 61
    Bouillon R, Van Cromphaut S, Carmeliet G. Intestinal calcium absorption: Molecular vitamin D mediated mechanisms. J Cell Biochem. 2003; 88: 3329.
  • 62
    Lee GS, Choi KC, Jeung EB. Glucocorticoids differentially regulate expression of duodenal and renal calbindin-D9k through glucocorticoid receptor-mediated pathway in mouse model. Am J Physiol Endocrinol Metab. 2006; 290: E299307.
  • 63
    Peng JB, Chen XZ, Berger UV, Vassilev PM, Brown EM, Hediger MA. A rat kidney-specific calcium transporter in the distal nephron. J Biol Chem. 2000; 275: 2818694.
  • 64
    Lledo PM, Somasundaram B, Morton AJ, Emson PC, Mason WT. Stable transfection of calbindin-D28k into the GH3 cell line alters calcium currents and intracellular calcium homeostasis. Neuron. 1992; 9: 94354.
  • 65
    Wu MJ, Lai LW, Lien YH. Effect of calbindin-D28K on cyclosporine toxicity in cultured renal proximal tubular cells. J Cell Physiol. 2004; 200: 3959.
  • 66
    Bastl CP, Schulman G, Cragoe EJ, Jr. Low-dose glucocorticoids stimulate electroneutral NaCl absorption in rat colon. Am J Physiol. 1989; 257: F102738.
  • 67
    Beaulieu JF, Calvert R. Influences of dexametha-sone on the maturation of fetal mouse intestinal mucosa in organ culture. Comp Biochem Physiol A. 1985; 82: 915.
  • 68
    Sheppard KE, Li KX, Autelitano DJ. Corticosteroid receptors and 11beta-hydroxysteroid dehydrogenase isoforms in rat intestinal epithelia. Am J Physiol. 1999; 277: G5417.
  • 69
    Farman N. Receptors of steroid hormones in the kidney. Pathol Biol. 1988; 36: 83945.
  • 70
    Farman N, Oblin ME, Lombes M, Delahaye F, Westphal HM, Bonvalet JP, Gasc JM. Immunolocalization of gluco- and mineralocorticoid receptors in rabbit kidney. Am J Physiol. 1991; 260: C22633.
  • 71
    Fujimoto N, Igarashi K, Kanno J, Honda H, Inoue T. Identification of estrogen-responsive genes in the GH3 cell line by cDNA microarray analysis. J Steroid Biochem Mol Biol. 2004; 91: 1219.
  • 72
    Nguyen TH, Lee GS, Ji YK, Choi KC, Lee CK, Jeung EB. A calcium binding protein, calbindin-D9k, is mainly regulated by estrogen in the pituitary gland of rats during estrous cycle. Brain Res Mol Brain Res. 2005; 141: 16673.
  • 73
    Elger W, Bartley J, Schneider B, Kaufmann G, Schubert G, Chwalisz K. Endocrine pharmacological characterization of progesterone antagonists and progesterone receptor modulators with respect to PR-agonistic and antagonistic activity. Steroids. 2000;65:71323.
  • 74
    Lee GS, Kim HJ, Jung YW, Choi KC, Jeung EB. Estrogen receptor alpha pathway is involved in the regulation of Calbindin-D9k in the uterus of immature rats. Toxicol Sci. 2005; 84: 2707.
  • 75
    Kuiper GG, Carlsson B, Grandien K, Enmark E, Haggblad J, Nilsson S, Gustafsson JA. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology. 1997; 138: 86370.
  • 76
    Pelletier G. Localization of androgen and estrogen receptors in rat and primate tissues. Histol Histopathol. 2000; 15: 126170.
  • 77
    Michels KM, Lee WH, Seltzer A, Saavedra JM, Bondy CA. Up-regulation of pituitary [125I]insulin-like growth factor-I (IGF-I) binding and IGF binding protein-2 and IGF-I gene expression by estrogen. Endocrinology. 1993; 132: 239.
  • 78
    Mormede P, Baird A. Estrogens, cyclic adenosine 3′, 5′-monophosphate, and phorbol esters modulate the prolactin response of GH3 cells to basic fibroblast growth factor. Endocrinology. 1988; 122: 226571.
  • 79
    Lee GS, Choi KC, Kim HJ, Jeung EB. Effect of genistein as a selective estrogen receptor beta agonist on the expression of Calbindin-D9k in the uterus of immature rats. Toxicol Sci. 2004; 82: 4517.
  • 80
    An BS, Choi KC, Lee GS, Leung PC, Jeung EB. Complex regulation of Calbindin-D9k in the mouse placenta and extra-embryonic membrane during mid-and late pregnancy. Mol Cell Endocrinol. 2004; 214: 3952.
  • 81
    Jung YW, Hong EJ, Choi KC, Jeung EB. Novel progestogenic activity of environmental endocrine disruptors in the upregulation of calbindin-D9k in an immature mouse model. Toxicol Sci. 2005; 83: 7888.
  • 82
    Lee CT, Shang S, Lai LW, Yong KC, Lien YH. Effect of thiazide on renal gene expression of apical calcium channels and calbindins. Am J Physiol Renal Physiol. 2004; 287: F116470.
  • 83
    Choi KC, Leung PC, Jeung EB. Biology and physiology of Calbindin-D9k in female reproductive tissues: involvement of steroids and endocrine disruptors. Reprod Biol Endocrinol. 2005; 3: 66.
  • 84
    Lee GS, Choi KC, Han HJ, Jeung EB. The classical and a non-classical pathways associated with NF-kappaB are involved in estrogen-medicated regulation of Calbindin-D9k gene in rat pituitary cells. Mol Cell Endocrinol. 2007; 277: 4250.
  • 85
    Wilson ME, Price RH, Jr., Handa RJ. Estrogen receptor-beta messenger ribonucleic acid expression in the pituitary gland. Endocrinology. 1998; 139: 51516.
  • 86
    Luu KC, Nie GY, Salamonsen LA. Endometrial cal-bindins are critical for embryo implantation: evidence from in vivo use of morpholino antisense oligonu-cleotides. Proc Natl Acad Sci USA. 2004; 101: 802833.
  • 87
    McDonnell DP. The molecular determinants of estrogen receptor pharmacology. Maturitas. 2004; 48: S712.
  • 88
    McDonnell DP. The molecular pharmacology of estrogen receptor modulators: implications for the treatment of breast cancer. Clin Cancer Res. 2005; 11: 71s7s.
  • 89
    Pochet R, Blachier F, Malaisse W, Parmentier M, Pasteels B, Pohl V, Resibois A, Rogers J, Roman A. Calbindin-D28 in mammalian brain, retina, and endocrine pancreas:immunohistochemical comparison with calretinin. Adv Exp Med Biol. 1989; 55: 3543.