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  • 1
    Li L, Rose P, Moore PK. Hydrogen sulfide and cell signaling. Annu Rev Pharmacol Toxicol. 2011; 51: 16987.
  • 2
    Whiteman M, Moore PK. Hydrogen sulfide and the vasculature: a novel vasculoprotective entity and regulator of nitric oxide bioavailability? J Cell Mol Med. 2009; 13: 488507.
  • 3
    Whiteman M, Winyard PG. Hydrogen sulfide and inflammation: the good, the bad, the ugly and the promising. Expert Rev Clin Pharmacol. 2011; 4: 1332.
  • 4
    Zhi L, Ang AD, Zhang H, et al. Hydrogen sulfide induces the synthesis of proinflammatory cytokines in human monocyte cell line U937 via the ERK-NF-kappaB pathway. J Leukoc Biol. 2007; 81: 132232.
  • 5
    Zhang H, Moochhala SM, Bhatia M. Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis. J Immunol. 2008; 181: 432031.
  • 6
    Zhang H, Zhi L, Moore PK, et al. Role of hydrogen sulfide in cecal ligation and puncture-induced sepsis in the mouse. Am J Physiol Lung Cell Mol Physiol. 2006; 290: L1193–201.
  • 7
    Bhatia M, Zhi L, Zhang H, et al. Role of substance P in hydrogen sulfide-induced pulmonary inflammation in mice. Am J Physiol Lung Cell Mol Physiol. 2006; 291: L896–904.
  • 8
    Li L, Bhatia M, Zhu YZ, et al. Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse. FASEB J. 2005; 19: 11968.
  • 9
    Whiteman M, Haigh R, Tarr JM, et al. Detection of hydrogen sulfide in plasma and knee-joint synovial fluid from rheumatoid arthritis patients: relation to clinical and laboratory measures of inflammation. Ann N Y Acad Sci. 2010; 1203: 14650.
  • 10
    Kloesch B, Liszt M, Broell J. H2S transiently blocks IL-6 expression in rheumatoid arthritic fibroblast-like synoviocytes and deactivates p44/42 mitogen-activated protein kinase. Cell Biol Int. 2010; 34: 47784.
  • 11
    Whiteman M, Li L, Rose P, et al. The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxid Redox Signal. 2010; 12: 114754.
  • 12
    Andruski B, McCafferty DM, Ignacy T, et al. Leukocyte trafficking and pain behavioral responses to a hydrogen sulfide donor in acute monoarthritis. Am J Physiol Regul Integr Comp Physiol. 2008; 295: R814–20.
  • 13
    Caplan AI, Elyaderani M, Mochizuki Y, et al. Principles of cartilage repair and regeneration. Clin Orthop Relat Res. 1997: 254–69.
  • 14
    Yoo JU, Barthel TS, Nishimura K, et al. The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells. J Bone Joint Surg Am. 1998; 80: 174557.
  • 15
    Alsalameh S, Amin R, Gemba T, et al. Identification of mesenchymal progenitor cells in normal and osteoarthritic human articular cartilage. Arthritis Rheum. 2004; 50: 152232.
  • 16
    Marinova-Mutafchieva L, Taylor P, Funa K, et al. Mesenchymal cells expressing bone morphogenetic protein receptors are present in the rheumatoid arthritis joint. Arthritis Rheum. 2000; 43: 204655.
  • 17
    Blanco FJ, Guitian R, Vazquez-Martul E, et al. Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology. Arthritis Rheum. 1998; 41: 2849.
  • 18
    Thomas CM, Whittles CE, Fuller CJ, et al. Variations in chondrocyte apoptosis may explain the increased prevalence of osteoarthritis in some joints. Rheumatol Int. 2010; doi: 10.1007/s00296-010-1471-9.
  • 19
    Kim HA, Song YW. Apoptotic chondrocyte death in rheumatoid arthritis. Arthritis Rheum. 1999; 42: 152837.
  • 20
    Saito S, Murakoshi K, Kotake S, et al. Granzyme B induces apoptosis of chondrocytes with natural killer cell-like cytotoxicity in rheumatoid arthritis. J Rheumatol. 2008; 35: 193243.
  • 21
    Polzer K, Schett G, Zwerina J. The lonely death: chondrocyte apoptosis in TNF-induced arthritis. Autoimmunity. 2007; 40: 3336.
  • 22
    Liu H, Pope RM. The role of apoptosis in rheumatoid arthritis. Curr Opin Pharmacol. 2003; 3: 31722.
  • 23
    Moodley D, Mody G, Patel N, et al. Mitochondrial depolarisation and oxidative stress in rheumatoid arthritis patients. Clin Biochem. 2010; 41: 1396401.
  • 24
    Miesel R, Murphy MP, Kroger H. Enhanced mitochondrial radical production in patients which rheumatoid arthritis correlates with elevated levels of tumour necrosis factor alpha in plasma. Free Radic Res. 1996; 25: 1619.
  • 25
    Blanco FJ, Rego I, Ruiz-Romero C. The role of mitochondria in osteoarthritis. Nat Rev Rheumatol. 2011; 7: 1619.
  • 26
    Whiteman M, Armstrong JS, Cheung NS, et al. Peroxynitrite mediates calcium-dependent mitochondrial dysfunction and cell death via activation of calpains. FASEB J. 2004; 18: 13957.
  • 27
    Thomas CM, Fuller CJ, Whittles CE, et al. Chondrocyte death by apoptosis is associated with cartilage matrix degradation. Osteoarthritis Cartilage. 2007; 15: 2734.
  • 28
    Yatsugi N, Tsukazaki T, Osaki M, et al. Apoptosis of articular chondrocytes in rheumatoid arthritis and osteoarthritis: correlation of apoptosis with degree of cartilage destruction and expression of apoptosis-related proteins of p53 and c-myc. J Orthop Sci. 2000; 5: 1506.
  • 29
    Cillero-Pastor B, Caramés B, Lires-Deán M, et al. Mitochondrial dysfunction activates cyclooxygenase 2 expression in cultured normal human chondrocytes. Arthritis Rheum. 2008; 58: 240919.
  • 30
    Whiteman M, Spencer JP, Zhu YZ, et al. Peroxynitrite-modified collagen-II induces p38/ERK and NF-kappaB-dependent synthesis of prostaglandin E2 and nitric oxide in chondrogenically differentiated mesenchymal progenitor cells. Osteoarthritis Cartilage. 2006; 14: 46070.
  • 31
    Whiteman M, Chu SH, Siau JL, et al. The pro-inflammatory oxidant hypochlorous acid induces Bax-dependent mitochondrial permeabilisation and cell death through AIF-/EndoG-dependent pathways. Cell Signal. 2007; 19: 70514.
  • 32
    Schantz J-T, Ng KWA. Manual for primary human cell culture. Singapore: World Scientific; 2004. p. 23–46.
  • 33
    Li L, Salto-Tellez M, Tan CH, et al. GYY4137, a novel hydrogen sulfide-releasing molecule, protects against endotoxic shock in the rat. Free Radic Biol Med. 2009; 47: 10313.
  • 34
    Li L, Whiteman M, Guan YY, et al. Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide. Circulation. 2008; 117: 235160.
  • 35
    Sanchez C, Mateus MM, Defresne MP, et al. Metabolism of human articular chondrocytes cultured in alginate beads. Longterm effects of interleukin 1beta and nonsteroidal antiinflammatory drugs. J Rheumatol. 2002; 29: 77282.
  • 36
    Legendre F, Bauge C, Roche R, et al. Chondroitin sulfate modulation of matrix and inflammatory gene expression in IL-1beta-stimulated chondrocytes: study in hypoxic alginate bead cultures. Osteoarthritis Cartilage. 2008; 16: 10514.
  • 37
    Armstrong JS, Whiteman M, Rose P, et al. The coenzyme Q10 analog decylubiquinone inhibits the redox-activated mitochondrial permeability transition: role of mitcohondrial [correction mitochondrial] complex III. J Biol Chem. 2003; 278: 4907984.
  • 38
    Whiteman M, Rose P, Siau JL, et al. Hypochlorous acid-mediated mitochondrial dysfunction and apoptosis in human hepatoma HepG2 and human foetal liver cells: role of mitochondrial permeability transition. Free Radic Biol Med. 2005; 38: 157184.
  • 39
    Pattison DJ, Winyard PG. Dietary antioxidants in inflammatory arthritis: do they have any role in etiology or therapy? Nat Clin Pract Rheumatol. 2008; 4: 5906.
  • 40
    Blanco FJ, Ochs RL, Schwarz H, et al. Chondrocyte apoptosis induced by nitric oxide. Am J Pathol. 1995; 146: 7585.
  • 41
    Asada S, Fukuda K, Nishisaka F, et al. Hydrogen peroxide induces apoptosis of chondrocytes: involvement of calcium ion and extracellular signal-regulated protein kinase. Inflamm Res. 2001; 50: 1923.
  • 42
    Vaillancourt F, Fahmi H, Shi Q, et al. 4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase. Arthritis Res Ther. 2008; 10: R107.
  • 43
    Blanco FJ, Lopez-Armada MJ, Maneiro E. Mitochondrial dysfunction in osteoarthritis. Mitochondrion. 2004; 4: 71528.
  • 44
    Whiteman M, Rose P, Siau JL, et al. Nitrite-mediated protection against hypochlorous acid-induced chondrocyte toxicity: a novel cytoprotective role of nitric oxide in the inflamed joint?Arthritis Rheum. 2003; 48: 314050.
  • 45
    Maneiro E, Lopez-Armada MJ, de Andres MC, et al. Effect of nitric oxide on mitochondrial respiratory activity of human articular chondrocytes. Ann Rheum Dis. 2005; 64: 38895.
  • 46
    Whiteman M, Hooper DC, Scott GS, et al. Inhibition of hypochlorous acid-induced cellular toxicity by nitrite. Proc Natl Acad Sci U S A. 2002; 99: 120616.
  • 47
    Bamborough P, Morse MA, Ray KP. Targeting IKKbeta for the treatment of rheumatoid arthritis. Drug News Perspect. 2010; 23: 48390.
  • 48
    Roman-Blas JA, Jimenez SA. Targeting NF-kappaB: a promising molecular therapy in inflammatory arthritis. Int Rev Immunol. 2008; 27: 35174.
  • 49
    Coulthard LR, White DE, Jones DL, et al. p38(MAPK): stress responses from molecular mechanisms to therapeutics. Trends Mol Med. 2009; 15: 36979.
  • 50
    Thalhamer T, McGrath MA, Harnett MM. MAPKs and their relevance to arthritis and inflammation. Rheumatology (Oxford). 2008; 47: 40914.
  • 51
    Yang G, Yang W, Wu L, et al. H2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells. J Biol Chem. 2007; 282: 1656776.
  • 52
    Adhikari S, Bhatia M. H2S-induced pancreatic acinar cell apoptosis is mediated via JNK and p38 MAP kinase. J Cell Mol Med. 2008; 12: 137483.
  • 53
    Li W, Jin HF, Liu D, et al. Hydrogen sulfide induces apoptosis of pulmonary artery smooth muscle cell in rats with pulmonary hypertension induced by high pulmonary blood flow. Chin Med J (Engl). 2009; 122: 30328.
  • 54
    Zhang JH, Dong Z, Chu L. Hydrogen sulfide induces apoptosis in human periodontium cells. J Periodontal Res. 2010; 45: 718.
  • 55
    Yu F, Zhao J, Tang CS, et al. Effect of synthesized GYY4137, a slowly releasing hydrogen sulfide donor, on cell viability and distribution of hydrogen sulfide in mice. Beijing Da Xue Xue Bao. 2010; 42: 4937.
  • 56
    Chiku T, Padovani D, Zhu W, et al. H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia. J Biol Chem. 2009; 284: 1160112.
  • 57
    Singh S, Padovani D, Leslie RA, et al. Relative contributions of cystathionine beta-synthase and gamma-cystathionase to H2S biogenesis via alternative trans-sulfuration reactions. J Biol Chem. 2009; 284: 2245766.
  • 58
    Maneiro E, Martin MA, de Andres MC, et al. Mitochondrial respiratory activity is altered in osteoarthritic human articular chondrocytes. Arthritis Rheum. 2003; 48: 7008.
  • 59
    Takahashi T, Kitaoka K, Ogawa Y, et al. Lysosomal dysfunction on hydrogen peroxide-induced apoptosis of osteoarthritic chondrocytes. Int J Mol Med. 2004; 14: 197200.
  • 60
    Beltowski J, Jamroz-Wisniewska A, Tokarzewska D. Hydrogen sulfide and its modulation in arterial hypertension and atherosclerosis. Cardiovasc Hematol Agents Med Chem. 2010; 8: 17386.
  • 61
    Lazzerini PE, Capecchi PL, Bisogno S, et al. Reduction in plasma homocysteine level in patients with rheumatoid arthritis given pulsed glucocorticoid treatment. Ann Rheum Dis. 2003; 62: 6945.
  • 62
    Giustarini D, Lorenzini S, Rossi R, et al. Altered thiol pattern in plasma of subjects affected by rheumatoid arthritis. Clin Exp Rheumatol. 2005; 23: 20512.
  • 63
    Bradley H, Waring RH, Emery P. Reduced thiol methyl transferase activity in red blood cell membranes from patients with rheumatoid arthritis. J Rheumatol. 1991; 18: 17879.
  • 64
    Sun Q, Collins R, Huang S, et al. Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S. J Biol Chem. 2009; 284: 307685.
  • 65
    Perry MM, Hui CK, Whiteman M, et al. Hydrogen sulfide inhibits proliferation and release of IL-8 from human airway smooth muscle cells. Am J Respir Cell Mol Biol. 2011; doi: 10.1165/rcmb.2010-0304OC.
  • 66
    Whiteman M, Li L, Kostetski I, et al. Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulfide. Biochem Biophys Res Commun. 2006; 343: 30310.
  • 67
    Whiteman M, Armstrong JS, Chu SH, et al. The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite ‘scavenger’?J Neurochem. 2004; 90: 7658.
  • 68
    Whiteman M, Cheung NS, Zhu YZ, et al. Hydrogen sulfide: a novel inhibitor of hypochlorous acid-mediated oxidative damage in the brain? Biochem Biophys Res Commun. 2005; 326: 7948.
  • 69
    Nagy P, Winterbourn CC. Rapid reaction of hydrogen sulfide with the neutrophil oxidant hypochlorous acid to generate polysulfides. Chem Res Toxicol. 2010; doi: 10.1021/tx100266a.
  • 70
    Tyagi N, Moshal KS, Sen U, et al. H2S protects against methionine-induced oxidative stress in brain endothelial cells. Antioxid Redox Signal. 2009; 11: 2533.
  • 71
    Muzaffar S, Shukla N, Bond M, et al. Exogenous hydrogen sulfide inhibits superoxide formation, NOX-1 expression and Rac1 activity in human vascular smooth muscle cells. J Vasc Res. 2008; 45: 5218.
  • 72
    Muellner MK, Schreier SM, Laggner H, et al. Hydrogen sulfide destroys lipid hydroperoxides in oxidized LDL. Biochem J. 2009; 420: 27781.
  • 73
    Schreier SM, Muellner MK, Steinkellner H, et al. Hydrogen sulfide scavenges the cytotoxic lipid oxidation product 4-HNE. Neurotox Res. 2010; 17: 24956.
  • 74
    Laggner H, Muellner MK, Schreier S, et al. Hydrogen sulfide: a novel physiological inhibitor of LDL atherogenic modification by HOCl. Free Radic Res. 2007; 41: 7417.
  • 75
    Carballal S, Trujillo M, Cuevasanta E, et al. Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest. Free Radic Biol Med. 2011; 50: 196205.
  • 76
    Kimura Y, Dargusch R, Schubert D, et al. Hydrogen sulfide protects HT22 neuronal cells from oxidative stress. Antioxid Redox Signal. 2006; 8: 66170.
  • 77
    Kimura Y, Kimura H. Hydrogen sulfide protects neurons from oxidative stress. FASEB J. 2004; 18: 11657.
  • 78
    Calvert JW, Elston M, Nicholson CK, et al. Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. Circulation. 2010; 122: 119.
  • 79
    Calvert JW, Jha S, Gundewar S, et al. Hydrogen sulfide mediates cardioprotection through Nrf2 signaling. Circ Res. 2009; 105: 36574.
  • 80
    Kloesch B, Liszt M, Steiner G, et al. Inhibitors of p38 and ERK1/2 MAPkinase and hydrogen sulfide block constitutive and IL-1beta-induced IL-6 and IL-8 expression in the human chondrocyte cell line C-28/I2. Rheumatol Int. 2010; doi: 101007/s00296–010-1682–0.