• 1
    Chen H, Tung YC, Li B, et al. Trophic factors counteract elevated FGF-2-induced inhibition of adult neurogenesis. Neurobiol Aging. 2007; 28: 114862.
  • 2
    HutterPaier B, Fruhwirth M, Grygar E, et al. Cerebrolysin(R) protects neurons from ischemia-induced loss of microtubule – associated protein 2. J Neural Transm Suppl. 1996; 46: 276.
  • 3
    Schwab M, Schaller R, Bauer R, et al. Morphofunctional effects of moderate forebrain ischemia combined with short-term hypoxia in rats – protective effects of Cerebrolysin. Exp Toxicol Pathol. 1997; 49: 2937.
  • 4
    Tatebayashi Y, Lee MH, Li L, et al. The dentate gyrus neurogenesis: a therapeutic target for Alzheimer's disease. Acta Neuropathol. 2003; 105: 22532.
  • 5
    Satou T, Itoh T, Tamai Y, et al. Neurotrophic effects of FPF-1070 (Cerebrolysin (R)) on cultured neurons from chicken embryo dorsal root ganglia, ciliary ganglia, and sympathetic trunks. J Neural Transm. 2000; 107: 125362.
  • 6
    FrancisTurner L, Valouskova V. Nerve growth factor and nootropic drug Cerebrolysin but not fibroblast growth factor can reduce spatial memory impairment elicited by fimbria-fornix transection: short-term study. Neurosci Lett. 1996; 202: 1936.
  • 7
    Ruther E, Ritter R, Apecechea M, et al. Efficacy of the peptidergic nootropic drug cerebrolysin in patients with senile dementia of the Alzheimer-type (SDAT). Pharmacopsychiatry. 1994; 27: 3240.
  • 8
    Wei ZH, He QB, Wang H, et al. Meta-analysis: the efficacy of nootropic agent Cerebrolysin in the treatment of Alzheimer's disease. J Neural Transm. 2007; 114: 62934.
  • 9
    Kletsas D, Barbieri D, Stathakos D, et al. The highly reducing sugar 2-deoxy-D-ribose induces apoptosis in human fibroblasts by reduced glutathione depletion and cytoskeletal disruption. Biochem Biophys Res Commun. 1998; 243: 41625.
  • 10
    Nicoletti I, Migliorati G, Pagliacci MC, et al. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow-cytometry. J Immunol Methods. 1991; 139: 2719.
  • 11
    Formichi P, Battisti C, Tripodi SA, et al. Apoptotic response and cell cycle transition in ataxia telangiectasia cells exposed to oxidative stress. Life Sci. 2000; 66: 1893903.
  • 12
    lHartbauer M, Hutter-Paier B, Skofitsch G, et al. Antiapoptotic effects of the peptidergic drug Cerebrolysin on primary cultures of embryonic chick cortical neurons. J Neural Transm. 2001; 108: 45973.
  • 13
    Gutmann B, Hutter-Paier B, Windisch M, et al. Long-term effects of cerebrolysin on spatial navigation: comparison of different treatment-schedules. Neurobiol Aging. 2002; 23: S86.
  • 14
    Onishchenko LS, Gaikova ON, Yanishevskii SN. Changes at the focus of experimental ischemic stroke treated with neuroprotective agents. Neurosci Behav Physiol. 2008; 38: 4954.
  • 15
    Wronski R, Kronawetter S, Hutter-Paier B, et al. A brain derived peptide preparation reduces the translation dependent loss of a cytoskeletal protein in primary cultured chicken neurons. J Neural Transm Suppl. 2000; 59: 26372.
  • 16
    Squier MKT, Miller ACK, Malkinson AM, et al. Calpain activaction in apoptosis. J Cell Physiol. 1994; 159: 22937.
  • 17
    Hutter-Paier B, Grygar E, Fruhwirth M, et al. Further evidence that Cerebrolysin(R) protects cortical neurons from neurodegeneration in vitro. J Neural Transm Suppl. 1998; 53: 36372.
  • 18
    Hutter-Paier B, Steiner E, Windisch M. Cerebrolysin(R) protects isolated cortical neurons from neurodegeneration after brief histotoxic hypoxia. J Neural Transm Suppl. 1998; 53: 35161.
  • 19
    Formichi P, Radi E, Battisti C, et al. Apoptosis in CADASIL: an in vitro study of lymphocytes and fibroblasts from a cohort of Italian patients. J Cell Physiol. 2009; 219: 494502.