EFFECT of SYMPATHETIC DENERVATION ON CHRONIC COLD INJURIES IN RABBIT BRAIN

A Microangiographical and Histological Study

Authors


Department of Neurosurgery, the University of Umeå, S-901 85, Umeå, Sweden.

ABSTRACT

Sympathetic denervation of the brain vessels was performed uni- or bilaterally in 13 adult rabbits, and cortical cold lesions were induced bilaterally 10–18 days afterwards. After a further 4–35 days the vascular and morphological changes in the lesion areas were studied histologically and with angiography. No difference was observed between the denervated and the non-denervated lesion areas. the results are discussed with regard to a proposed functional plasticity of the chronically denervated brain vessels and/or to possible changes in metabolic demands of the brain tissue.

Ancillary