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Motor neuron disease recovery associated with IV ceftriaxone and anti-Babesia therapy
Article first published online: 11 AUG 2006
DOI: 10.1111/j.1600-0404.2006.00727.x
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How to Cite
Harvey, W. T. and Martz, D. (2007), Motor neuron disease recovery associated with IV ceftriaxone and anti-Babesia therapy. Acta Neurologica Scandinavica, 115: 129–131. doi: 10.1111/j.1600-0404.2006.00727.x
Publication History
- Issue published online: 11 AUG 2006
- Article first published online: 11 AUG 2006
- Accepted for publication June 30, 2006
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Keywords:
- Borrelia;
- Babesia;
- motor neuron disease;
- amyotrophic lateral sclerosis;
- ceftriaxone;
- atovaquone
This report summarizes what we believe to be the first verifiable case of a significant and progressive motor neuron disease (MND) consistent with amyotrophic lateral sclerosis that resolved during treatment with i.v. ceftriaxone plus oral atovaquone and mefloquine. The rationale for use of these antibiotics was (i) positive testing for Borrelia burgdorferi and (ii) red blood cell ring forms consistent with Babesia species infection. The patient has continued to be free of MND signs and symptoms for 15 months, although some symptoms consistent with disseminated Borreliosis remain.