Pallidal deep brain stimulation in the treatment of Meige syndrome
Article first published online: 11 MAR 2008
Copyright © 2008 The Authors. Journal compilation © 2008 Blackwell Munksgaard
Acta Neurologica Scandinavica
Volume 118, Issue 3, pages 198–202, September 2008
How to Cite
Blomstedt, P., Tisch, S. and Hariz, M. I. (2008), Pallidal deep brain stimulation in the treatment of Meige syndrome. Acta Neurologica Scandinavica, 118: 198–202. doi: 10.1111/j.1600-0404.2008.00999.x
- Issue published online: 12 AUG 2008
- Article first published online: 11 MAR 2008
- Accepted for publication January 10, 2008
- Meige syndrome;
- pallidal stimulation
Background – Pallidal deep brain stimulation (DBS) of globus pallidus internus (Gpi) has emerged as an effective treatment for dystonia. The experience is however limited concerning focal dystonias and to date only a few cases of pallidal DBS in the treatment of Meige syndrome have been published.
Methods/results – We here present a patient with Meige syndrome in whom unilateral pallidal DBS failed to improve the axial symptoms, but bilateral stimulation resulted in a major improvement. The Burke-Fahn-Marsden score (BFM) improved by 71.5% and the patient’s blepharospasm was abolished.
Conclusions – The results suggest bilateral pallidal DBS may be an effective treatment for Meige syndrome.