Other members of the Study Group are listed in the Appendix.
Active and passive smoking and risk of Parkinson’s disease
Article first published online: 17 FEB 2010
Copyright © 2010 The Authors. Journal compilation © 2010 Blackwell Munksgaard
Acta Neurologica Scandinavica
Volume 122, Issue 6, pages 377–382, December 2010
How to Cite
Tanaka, K., Miyake, Y., Fukushima, W., Sasaki, S., Kiyohara, C., Tsuboi, Y., Yamada, T., Oeda, T., Miki, T., Kawamura, N., Sakae, N., Fukuyama, H., Hirota, Y., Nagai, M. and the Fukuoka Kinki Parkinson’s disease Study Group (2010), Active and passive smoking and risk of Parkinson’s disease. Acta Neurologica Scandinavica, 122: 377–382. doi: 10.1111/j.1600-0404.2010.01327.x
- Issue published online: 17 FEB 2010
- Article first published online: 17 FEB 2010
- Accepted for publication December 17, 2009
- case–control studies;
- Parkinson’s disease;
- passive smoking;
Tanaka K, Miyake Y, Fukushima W, Sasaki S, Kiyohara C, Tsuboi Y, Yamada T, Oeda T, Miki T, Kawamura N, Sakae N, Fukuyama H, Hirota Y, Nagai M, the Fukuoka Kinki Parkinson’s disease Study Group. Active and passive smoking and risk of Parkinson’s disease. Acta Neurol Scand: 2010: 122: 377–382. © 2010 The Authors Journal compilation © 2010 Blackwell Munksgaard.
Objective – To assess the association between active and passive smoking and the risk of Parkinson’s disease (PD), a case–control study with 249 PD patients and 369 controls was carried out in Japan.
Methods – Information on smoking was obtained through a self-administered questionnaire. Adjustment was made for age, sex, region of residence, educational level, and occupational exposure.
Results – Ever having smoked cigarettes was associated with a reduced risk of PD [adjusted odds ratio = 0.38; 95% confidence interval (CI): 0.24–0.59]. Risk for former smokers was intermediate between the high risk for never smokers and the low risk for current smokers. Adjusted odds ratios for former and current smokers were 0.51 (95% CI: 0.32–0.82) and 0.12 (95% CI: 0.05–0.26), respectively. There was an inverse dose-response gradient with pack-years smoked. No significant association was detected for passive smoking exposure.
Conclusion – Our results appear to confirm data from previous epidemiological studies.