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Prevalence of Parkinson’s disease and atypical parkinsonian syndromes in a rural Japanese district

Authors


Y. Osaki, MD, Department of Geriatrics, Cardiology and Neurology, Kochi Medical School, Nankoku 783-8505, Japan
Tel.: +81 888 80 2352
Fax: +81 888 80 2349
E-mail: yosaki@kochi-u.ac.jp

Abstract

Osaki Y, Morita Y, Kuwahara T, Miyano I, Doi Y. Prevalence of Parkinson’s disease and atypical parkinsonian syndromes in a rural Japanese district.
Acta Neurol Scand: 2011: 124: 182–187.
© 2010 John Wiley & Sons A/S.

Objectives –  To investigate the prevalence of Parkinson’s disease (PD) and atypical parkinsonian syndromes (APS) in a rural Japanese district.

Method –  Collaboration with the medical institutions, the long-term care insurance system facilities, and the public health office.

Results –  The crude prevalence rates were 175 per 100 000 (95% CI: 143–206) for PD, 18 (8–28) for progressive supranuclear palsy, 17 (7–26) for multiple system atrophy (MSA), and 9 (2–16) for corticobasal degeneration. The age-adjusted prevalence rates were 109 per 100 000 (88–134), 10 (2–17), 13 (4–21), and 6 (0–12), for each condition. There was a preponderance of women with PD and of men with APS. Nine of the 116 PD patients and 7 of the 29 APS patients were newly diagnosed in this study.

Conclusions –  There are high prevalence rates for PD and APS and suboptimal recognition of APS. This is the first epidemiological prevalence study of MSA from Japan.

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