Conflict of interest The authors have stated explicitly that there are no conflicts of interest in connection with this article.
MAIN RESEARCH ARTICLE
Maternal and neonatal outcomes following induction of labor: a cohort study
Article first published online: 15 NOV 2011
© 2011 The Authors Acta Obstetricia et Gynecologica Scandinavica© 2011 Nordic Federation of Societies of Obstetrics and Gynecology
Acta Obstetricia et Gynecologica Scandinavica
Volume 91, Issue 2, pages 198–203, February 2012
How to Cite
GRIVELL, R. M., REILLY, A. J., OAKEY, H., CHAN, A. and DODD, J. M. (2012), Maternal and neonatal outcomes following induction of labor: a cohort study. Acta Obstetricia et Gynecologica Scandinavica, 91: 198–203. doi: 10.1111/j.1600-0412.2011.01298.x
- Issue published online: 18 JAN 2012
- Article first published online: 15 NOV 2011
- Accepted manuscript online: 13 OCT 2011 10:45PM EST
- Received: 3 March 2011, Accepted: 5 October 2011
Objective. To evaluate maternal and neonatal outcomes associated with birth at term by week of gestational age and also by onset of labor. Design. Cohort study. Setting. A state-wide perinatal outcome database. Population. 28 626 women with spontaneous onset of labor, induction of labor for recognized indications and induction of labor for non-recognized indications. Methods. Cohort study utilizing a validated dataset comparing outcomes with type of onset of labor using a log binomial model. Main outcome measures. Cesarean section, assisted vaginal birth, important measures of maternal and neonatal morbidity. Results. Induction of labor for non-recognized indications was associated with a significantly increased risk of a range of outcomes, including cesarean section (RR 1.67, 95%CI 1.55–1.80). The lowest risk of adverse maternal and infant outcome occurred with birth between 38 and 39 weeks and with the spontaneous onset of labor. Conclusions. Induction of labor for non-recognized indications at term is associated with an increased risk of adverse outcomes. Caution is warranted with a liberal policy of induction of labor at term in an otherwise uncomplicated pregnancy.