Conflict of interest The authors have stated explicitly that there are no conflicts of interest in connection with this article.
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Maternal and neonatal outcomes following induction of labor: a cohort study
Article first published online: 15 NOV 2011
DOI: 10.1111/j.1600-0412.2011.01298.x
© 2011 The Authors Acta Obstetricia et Gynecologica Scandinavica© 2011 Nordic Federation of Societies of Obstetrics and Gynecology
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How to Cite
GRIVELL, R. M., REILLY, A. J., OAKEY, H., CHAN, A. and DODD, J. M. (2012), Maternal and neonatal outcomes following induction of labor: a cohort study. Acta Obstetricia et Gynecologica Scandinavica, 91: 198–203. doi: 10.1111/j.1600-0412.2011.01298.x
Publication History
- Issue published online: 18 JAN 2012
- Article first published online: 15 NOV 2011
- Accepted manuscript online: 13 OCT 2011 10:45PM EST
- Received: 3 March 2011, Accepted: 5 October 2011
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Keywords:
- Induction;
- labor;
- maternal;
- morbidity;
- neonatal
Abstract
Objective. To evaluate maternal and neonatal outcomes associated with birth at term by week of gestational age and also by onset of labor. Design. Cohort study. Setting. A state-wide perinatal outcome database. Population. 28 626 women with spontaneous onset of labor, induction of labor for recognized indications and induction of labor for non-recognized indications. Methods. Cohort study utilizing a validated dataset comparing outcomes with type of onset of labor using a log binomial model. Main outcome measures. Cesarean section, assisted vaginal birth, important measures of maternal and neonatal morbidity. Results. Induction of labor for non-recognized indications was associated with a significantly increased risk of a range of outcomes, including cesarean section (RR 1.67, 95%CI 1.55–1.80). The lowest risk of adverse maternal and infant outcome occurred with birth between 38 and 39 weeks and with the spontaneous onset of labor. Conclusions. Induction of labor for non-recognized indications at term is associated with an increased risk of adverse outcomes. Caution is warranted with a liberal policy of induction of labor at term in an otherwise uncomplicated pregnancy.