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Association of three different techniques to measure blood pressure in the first trimester with the development of hypertensive disorders of pregnancy
Article first published online: 14 JAN 2013
© 2013 The Authors © 2013 Nordic Federation of Societies of Obstetrics and Gynecology
Acta Obstetricia et Gynecologica Scandinavica
Volume 92, Issue 1, pages 53–60, January 2013
How to Cite
VOLLEBREGT, K. C., BOER, K., VAN DER POST, J. A. M. and WOLF, H. (2013), Association of three different techniques to measure blood pressure in the first trimester with the development of hypertensive disorders of pregnancy. Acta Obstetricia et Gynecologica Scandinavica, 92: 53–60. doi: 10.1111/j.1600-0412.2012.01510.x
- Issue published online: 14 JAN 2013
- Article first published online: 14 JAN 2013
- Accepted manuscript online: 6 AUG 2012 05:10PM EST
- Manuscript Accepted: 13 JUL 2012
- Manuscript Received: 15 JUL 2011
- Ambulatory blood pressure monitoring;
- blood pressure;
- continuous finger arterial pressure waveform registration;
It is not known whether automated devices for measuring blood pressure perform better than conventional sphygmomanometry in predicting preeclampsia. This study compares two different automated devices with conventional sphygmomanometry for their association with development of preeclampsia or gestational hypertension.
Prospective observational cohort study.
University hospital, Amsterdam, the Netherlands.
289 healthy normotensive women of whom 235 were nulliparous and 44 parous with preeclampsia in a previous pregnancy.
At 8–11 weeks of pregnancy, blood pressure was measured with two different automated devices (continuous finger arterial pressure waveform registration and ambulatory blood pressure monitoring) and with conventional sphygmomanometry.
Main outcome measures
Preeclampsia and gestational hypertension.
Blood pressure in the first trimester, as measured with all three methods, was significantly higher in women who developed preeclampsia or gestational hypertension. After adjustment for previous preeclampsia, the point estimate of the odds ratios for association with later preeclampsia for both automated devices were comparable and higher than for conventional sphygmomanometry; however, differences were not statistically significant. The odds ratio (95% confidence intervals) for every 1 mmHg pressure increase of mean arterial pressure was 1.08 (1.02–1.15) for sphygmomanometry, 1.17 (1.09–1.27) for finger arterial pressure waveform registration, and 1.17 (1.07–1.27) for ambulatory blood pressure monitoring. Results were comparable if preeclampsia and gestational hypertension were analyzed together.
Blood pressure in the first trimester was associated with the development of hypertensive disorders of pregnancy. No significant differences were found between measurements by automatic devices compared with conventional sphygmomanometry.