Conflict of interest The authors have stated explicitly that there are no conflicts of interest in connection with this article.
MAIN RESEARCH ARTICLE
Newborns of mothers with intellectual disability have a higher risk of perinatal death and being small for gestational age
Article first published online: 1 NOV 2012
© 2012 The Authors Acta Obstetricia et Gynecologica Scandinavica© 2012 Nordic Federation of Societies of Obstetrics and Gynecology
Acta Obstetricia et Gynecologica Scandinavica
Volume 91, Issue 12, pages 1409–1414, December 2012
How to Cite
HÖGLUND, B., LINDGREN, P. and LARSSON, M. (2012), Newborns of mothers with intellectual disability have a higher risk of perinatal death and being small for gestational age. Acta Obstetricia et Gynecologica Scandinavica, 91: 1409–1414. doi: 10.1111/j.1600-0412.2012.01537.x
Please cite this article as: Höglund B, Lindgren P, Larsson M. Newborns of mothers with intellectual disability have a higher risk of perinatal death and being small for gestational age. Acta Obstet Gynecol Scand 2012;91: DOI: 10.1111/j.1600-0412.2012.01537.x.
- Issue published online: 5 DEC 2012
- Article first published online: 1 NOV 2012
- Accepted manuscript online: 24 AUG 2012 05:35AM EST
- Received: 29 July 2011 Accepted: 11 August 2012
- Intellectual disability;
- national registers;
- newborn outcomes;
- perinatal death
Objective. To study mode of birth, perinatal health and death in children born to mothers with intellectual disability (ID) in Sweden. Design. Population-based register study. Setting. National registers; the National Patient Register linked to the Medical Birth Register. Sample. Children of first-time mothers with ID (n = 326; classified in the International Classification of Diseases 8–10) were identified and compared with 340 624 children of first-time mothers without ID or any other psychiatric diagnosis between 1999 and 2007. Methods. Population-based data were extracted from the National Patient Register and the Medical Birth Register. Main outcome measures. Mode of birth, preterm birth, small for gestational age, Apgar score, stillbirth and perinatal death. Results. Children born to mothers with ID were more often stillborn (1.2 vs. 0.3%) or died perinatally (1.8 vs. 0.4%) than children born to mothers without ID. They had a higher proportion of cesarean section birth (24.5 vs. 17.7%) and preterm birth (12.2 vs. 6.1%), were small for gestational age (8.4 vs. 3.1%) and had lower Apgar scores (<7 points at five minutes; 3.7 vs 1.5%) compared with children born to mothers without ID. Logistic regression adjusted for maternal characteristics confirmed an increased risk of small for gestational age (odds ratio 2.25), stillbirth (odds ratio 4.53) and perinatal death (odds ratio 4.25) in children born to mothers with ID. Conclusions. Unborn and newborn children of mothers with ID should be considered a risk group, and their mothers may need better individual-based care and support.